ArticleThe Plant cell2009
A single vegetative actin isovariant overexpressed under the control of multiple regulatory sequences is sufficient for normal Arabidopsis development.
Article in The Plant cell, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers.
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Who cites it
52 citing papers in PubMed, 119 citations in OpenAlex.
- Root hair initiation-dependent and -independent nuclear movements during root hair development inPlant signaling & behavior · 2026Article
- Actin Isovariant ACT2-Mediated Cellular Auxin Homeostasis Regulates Lateral Root Organogenesis in Arabidopsis thaliana.Cytoskeleton (Hoboken, N.J.) · 2026Article
- Two-step, long-distance nuclear migration guided by distinct actin networks prior to plant root hair formation.PNAS nexus · 2026Article
- Cytoskeletal control of development and environmental adaptation in plants.Science China. Life sciences · 2026Review
- Genome-wide identification and expression analysis of the actin gene family in soybean (Glycine max).Genetica · 2025Article
- Multiple Mechanisms to Regulate Actin Functions: "Fundamental" Versus Lineage-Specific Mechanisms and Hierarchical Relationships.Biomolecules · 2025Review
- Genome-Wide Profiling of the ACTIN Gene Family and Its Implications for Agronomic Traits inInternational journal of molecular sciences · 2024Article
- Dynamics of Actin Filaments Play an Important Role in Root Hair Growth under Low Potassium Stress inInternational journal of molecular sciences · 2024Article
- Actin-depolymerizing factors 8 and 11 promote root hair elongation at high pH.Plant communications · 2024Article
- Exploring the Role of the Plant Actin Cytoskeleton: From Signaling to Cellular Functions.International journal of molecular sciences · 2023Review
- Genome-Wide Identification and Expression Analysis of ACTIN Family Genes in the Sweet Potato and Its Two Diploid Relatives.International journal of molecular sciences · 2023Article
- Genome-Wide Association Study of Lint Percentage inInternational journal of molecular sciences · 2023Article
- Actin depolymerizing factor ADF7 inhibits actin bundling protein VILLIN1 to regulate root hair formation in response to osmotic stress in Arabidopsis.PLoS genetics · 2022Article
- Genome-wide transcriptome signatures of ant-farmedEcology and evolution · 2021Article
- Arabidopsis thaliana subclass I ACTIN DEPOLYMERIZING FACTORs and vegetative ACTIN2/8 are novel regulators of endoreplication.Journal of plant research · 2021Article
- Actin Isovariant ACT7 Modulates Root Thermomorphogenesis by Altering Intracellular Auxin Homeostasis.International journal of molecular sciences · 2021Article
- Microtubule Dynamics Plays a Vital Role in Plant Adaptation and Tolerance to Salt Stress.International journal of molecular sciences · 2021Article
- Bundling up the Role of the Actin Cytoskeleton in Primary Root Growth.Frontiers in plant science · 2021Review
- Lipid Body Dynamics in Shoot Meristems: Production, Enlargement, and Putative Organellar Interactions and Plasmodesmal Targeting.Frontiers in plant science · 2021Article
- Auxin-induced actin cytoskeleton rearrangements require AUX1.The New phytologist · 2020Article
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3 authors at 1 institution in 1 country.
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Abstract
The relative significance of gene regulation and protein isovariant differences remains unexplored for most gene families, particularly those participating in multicellular development. Arabidopsis thaliana encodes three vegetative actins, ACT2, ACT7, and ACT8, in two ancient and highly divergent subclasses. Mutations in any of these differentially expressed actins revealed only mild phenotypes. However, double mutants were extremely dwarfed, with altered cell and organ morphology and an aberrant F-actin cytoskeleton (e.g., act2-1 act7-4 and act8-2 act7-4) or totally root-hairless (e.g., act2-1 act8-2). Our studies suggest that the three vegetative actin genes and protein isovariants play distinct subclass-specific roles during plant morphogenesis. For example, during root development, ACT7 was involved in root growth, epidermal cell specification, cell division, and root architecture, and ACT2 and ACT8 were essential for root hair tip growth. Also, genetic complementation revealed that the ACT2 and ACT8 isovariants, but not ACT7, fully rescued the root hair growth defects of single and double mutants. Moreover, we synthesized fully normal plants overexpressing the ACT8 isovariant from multiple actin regulatory sequences as the only vegetative actin in the act2-1 act7-4 background. In summary, it is evident that differences in vegetative actin gene regulation and the diversity in actin isovariant sequences are essential for normal plant development.
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