ReviewTranslational research : the journal of laboratory and clinical medicine2009
Asbestos-induced lung diseases: an update.
Review in Translational research : the journal of laboratory and clinical medicine, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 85 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
85 citing papers in PubMed, 2 syntheses or guidelines pooled it, 248 citations in OpenAlex.
- Examining the Environmental Ramifications of Asbestos Fiber Movement Through the Water-Soil Continuum: A Review.International journal of environmental research and public health · 2025Pooled it
- Additive Synergism between Asbestos and Smoking in Lung Cancer Risk: A Systematic Review and Meta-Analysis.PloS one · 2015Pooled it
- Naturally occurring asbestos and its possible environmental and health implications in the Basilicata region (Southern Italy).Environmental geochemistry and health · 2026Article
- Flow imaging microscopy-based method for rapid, high-throughput measurement of fiber count and length distributions in air.Environmental science. Processes & impacts · 2026Article
- Comparative Gene Expression Analysis of Malignant Mesothelioma and Lung Adenocarcinomas Induced by Multi-Walled Carbon Nanotube-7 and Double-Walled Carbon Nanotubes in Rats: Distinct Molecular Signatures and Canonical Pathways.Nanomaterials (Basel, Switzerland) · 2025Article
- Global burden of lung cancer attributable to occupational asbestos exposure: 1990 to 2021.Environmental health : a global access science source · 2025Article
- Mortality and Cancer Incidence After Exposure to Blue Asbestos in Childhood: A Further 10 Years of Follow-Up.American journal of industrial medicine · 2025Article
- Depressive and Anxiety Symptoms Among Patients with Asbestos-Related Diseases in Korea.Toxics · 2025Article
- Mesothelioma Cases in the World Trade Center Survivors.Annals of case reports · 2024Article
- Fleischner Society: Glossary of Terms for Thoracic Imaging.Radiology · 2024Review
- Environmental Causes of Idiopathic Pulmonary Fibrosis.International journal of molecular sciences · 2023Review
- Dissolution Reaction and Surface Modification of UICC Amosite in Mimicked Gamble's Solution: A Step towards Filling the Gap between Asbestos Toxicity and Its Crystal Chemical Features.Nanomaterials (Basel, Switzerland) · 2023Article
- APE-1/Ref-1 Inhibition Blocks Malignant Pleural Mesothelioma Cell Proliferation and Migration: Crosstalk between Oxidative Stress and Epithelial Mesenchymal Transition (EMT) in Driving Carcinogenesis and Metastasis.International journal of molecular sciences · 2023Article
- Artificial intelligence-based diagnosis of asbestosis: analysis of a database with applicants for asbestosis state aid.European radiology · 2023Article
- Synthesis of Ni-Doped Tremolite Fibers to Help Clarify the Aetiology of the Cytotoxic Outcome of Asbestos.Nanomaterials (Basel, Switzerland) · 2023Article
- Disease Latency according to Asbestos Exposure Characteristics among Malignant Mesothelioma and Asbestos-Related Lung Cancer Cases in South Korea.International journal of environmental research and public health · 2022Article
- Curcuminoids as Modulators of EMT in Invasive Cancers: A Review of Molecular Targets With the Contribution of Malignant Mesothelioma Studies.Frontiers in pharmacology · 2022Review
- The Epithelial-to-Mesenchymal Transition (EMT) in the Development and Metastasis of Malignant Pleural Mesothelioma.International journal of molecular sciences · 2021Review
- Lung cancer risk in never-smokers: An overview of environmental and genetic factors.Chinese journal of cancer research = Chung-kuo yen cheng yen chiu · 2021Article
- Long Noncoding RNAInternational journal of molecular sciences · 2021Article
25 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
Abstract
Asbestos causes asbestosis (pulmonary fibrosis caused by asbestos inhalation) and malignancies (bronchogenic carcinoma and mesothelioma) by mechanisms that are not fully elucidated. Despite a dramatic reduction in asbestos use worldwide, asbestos-induced lung diseases remain a substantial health concern primarily because of the vast amounts of fibers that have been mined, processed, and used during the 20th century combined with the long latency period of up to 40 years between exposure and disease presentation. This review summarizes the important new epidemiologic and pathogenic information that has emerged over the past several years. Whereas the development of asbestosis is directly associated with the magnitude and duration of asbestos exposure, the development of a malignant clone of cells can occur in the setting of low-level asbestos exposure. Emphasis is placed on the recent epidemiologic investigations that explore the malignancy risk that occurs from nonoccupational, environmental asbestos exposure. Accumulating studies are shedding light on novel mechanistic pathways by which asbestos damages the lung. Attention is focused on the importance of alveolar epithelial cell (AEC) injury and repair, the role of iron-derived reactive oxygen species (ROS), and apoptosis by the p53- and mitochondria-regulated death pathways. Furthermore, recent evidence underscores crucial roles for specific cellular signaling pathways that regulate the production of cytokines and growth factors. An evolving role for epithelial-mesenchymal transition (EMT) is also reviewed. The translational significance of these studies is evident in providing the molecular basis for developing novel therapeutic strategies for asbestos-related lung diseases and, importantly, other pulmonary diseases, such as interstitial pulmonary fibrosis and lung cancer.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.