ReviewCurrent opinion in structural biology2009
The long and the short of riboswitches.
Review in Current opinion in structural biology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 57 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
57 citing papers in PubMed.
- Structural basis for ligand recognition in the tobramycin riboswitch.Nucleic acids research · 2025Article
- Thermodynamic compensation to temperature extremes in B. subtilis vs T. maritima lysine riboswitches.Biophysical journal · 2024Article
- Riboswitch Distribution in the Human Gut Microbiome Reveals Common Metabolite Pathways.The journal of physical chemistry. B · 2024Article
- Non-covalent dyes in microscale thermophoresis for studying RNA ligand interactions and modifications.Chemical science · 2023Article
- Cobalamin riboswitches exhibit a broad range of ability to discriminate between methylcobalamin and adenosylcobalamin.The Journal of biological chemistry · 2017Article
- Riboswitch diversity and distribution.RNA (New York, N.Y.) · 2017Article
- Long-Range Interactions in Riboswitch Control of Gene Expression.Annual review of biophysics · 2017Review
- Advancement of the Emerging Field of RNA Nanotechnology.ACS nano · 2017Review
- Differential regulation of riboflavin supply genes inGut pathogens · 2017Article
- Novel riboswitch-binding flavin analog that protects mice against Clostridium difficile infection without inhibiting cecal flora.Antimicrobial agents and chemotherapy · 2015Article
- RNA quaternary structure and global symmetry.Trends in biochemical sciences · 2015Review
- Themes and variations in riboswitch structure and function.Biochimica et biophysica acta · 2014Review
- Evolutionary Origin and Conserved Structural Building Blocks of Riboswitches and Ribosomal RNAs: Riboswitches as Probable Target Sites for Aminoglycosides Interaction.Advanced pharmaceutical bulletin · 2014Article
- On the importance of cotranscriptional RNA structure formation.RNA (New York, N.Y.) · 2013Review
- Eukaryotic TPP riboswitch regulation of alternative splicing involving long-distance base pairing.Nucleic acids research · 2013Article
- Article
- RNA modularity for synthetic biology.F1000prime reports · 2013Review
- Folding path of P5abc RNA involves direct coupling of secondary and tertiary structures.Nucleic acids research · 2012Article
- Molecular recognition and function of riboswitches.Current opinion in structural biology · 2012Review
- Basis for ligand discrimination between ON and OFF state riboswitch conformations: the case of the SAM-I riboswitch.RNA (New York, N.Y.) · 2012Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
Abstract
Regulatory mRNA elements or riboswitches specifically control the expression of a large number of genes in response to various cellular metabolites. The basis for selectivity of regulation is programmed in the evolutionarily conserved metabolite-sensing regions of riboswitches, which display a plethora of sequence and structural variants. Recent X-ray structures of two distinct SAM riboswitches and the sensing domains of the Mg(2+), lysine, and FMN riboswitches have uncovered novel recognition principles and provided molecular details underlying the exquisite specificity of metabolite binding by RNA. These and earlier structures constitute the majority of widespread riboswitch classes and, together with riboswitch folding studies, improve our understanding of the mechanistic principles involved in riboswitch-mediated gene expression control.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.