ArticleJournal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology2009
Octopamine and tyramine modulate pheromone-sensitive olfactory sensilla of the hawkmoth Manduca sexta in a time-dependent manner.
Article in Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
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Who cites it
30 citing papers in PubMed, 53 citations in OpenAlex.
- Transcriptomic investigation of agonistic behaviors of boxer shrimps (Stenopus species): insights into the potential neural signaling roles of dopamine and acetylcholine.BMC genomics · 2026Article
- Hawkmoth Pheromone Transduction Involves G-Protein-Dependent Phospholipase Cβ Signaling.eNeuro · 2025Article
- The complex neurochemistry of the cockroach antennal heart.Cell and tissue research · 2024Article
- Hearing of malaria mosquitoes is modulated by a beta-adrenergic-like octopamine receptor which serves as insecticide target.Nature communications · 2023Article
- The auditory efferent system in mosquitoes.Frontiers in cell and developmental biology · 2023Review
- Modulation of the NO-cGMP pathway has no effect on olfactory responses in theFrontiers in cellular neuroscience · 2023Article
- Genetic mechanisms modulating behaviour through plastic chemosensory responses in insects.Molecular ecology · 2023Review
- G protein-coupled receptors as candidates for modulation and activation of the chemical senses in decapod crustaceans.PloS one · 2021Article
- Timing of male territorial flight and foraging of the large carpenter bee Xylocopa appendiculata related to serotonin in the brain.Die Naturwissenschaften · 2020Article
- Responsiveness to Sugar Solutions in the MothFrontiers in physiology · 2019Article
- Octopaminergic innervation and a neurohaemal release site in the antennal heart of the locust Schistocerca gregaria.Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology · 2018Article
- The Diacylglycerol Analogs OAG and DOG Differentially Affect Primary Events of Pheromone Transduction in the HawkmothFrontiers in cellular neuroscience · 2018Article
- Biogenic Amines in Insect Antennae.Frontiers in systems neuroscience · 2017Review
- Octopamine and tyramine respectively regulate attractive and repulsive behavior in locust phase changes.Scientific reports · 2015Article
- Differential Octopaminergic Modulation of Olfactory Receptor Neuron Responses to Sex Pheromones in Heliothis virescens.PloS one · 2015Article
- Octopamine regulates antennal sensory neurons via daytime-dependent changes in cAMP and IP3 levels in the hawkmoth Manduca sexta.PloS one · 2015Article
- Article
- The role of the coreceptor Orco in insect olfactory transduction.Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology · 2013Review
- Octopamine modulates activity of neural networks in the honey bee antennal lobe.Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology · 2013Article
- In situ tip-recordings found no evidence for an Orco-based ionotropic mechanism of pheromone-transduction in Manduca sexta.PloS one · 2013Article
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In moths octopamine improved pheromone-dependent mate search time dependently. In the nocturnal hawkmoth Manduca sexta long-term tip recordings of trichoid sensilla were performed to investigate whether biogenic amines modulate pheromone transduction time dependently. At three Zeitgebertimes octopamine, tyramine and the octopamine antagonist epinastine were applied during non-adapting pheromone-stimulation. At ZT 8-11, during the photophase, when sensilla were adapted, octopamine and to a lesser extent tyramine increased the bombykal-dependent sensillar potential amplitude and initial action potential (AP) frequency. In addition, during the photophase, when sensilla are less able to resolve pheromone pulses, octopamine rendered pheromone responses more phasic and sensitive, and raised the spontaneous AP frequency. During the late scotophase, at ZT 22-1, when the antenna appeared maximally sensitized for pheromone pulse detection and endogenous octopamine levels are high, exogenously applied octopamine was ineffective. Epinastine blocked the pheromone-dependent AP response at ZT 8-11 and slightly affected it at ZT 22-1, while it had no effect on the sensillar potential amplitude. Epinastine decreased the spontaneous AP activity during photophase and scotophase and rendered pheromone responses more tonic in the scotophase. We hypothesize that the presence of octopamine in the antenna is obligatory for the detection of intermittent pheromone pulses at all Zeitgebertimes.
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