ArticleRheumatology international2009
Systemic lupus erythematosus in Egyptian children.
Article in Rheumatology international, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed.
- Neuropsychiatric Systemic Lupus Erythematosus in Children: A Scoping Review.Open access rheumatology : research and reviews · 2026Review
- Article
- Circulating prolactin level in Juvenile Systemic Lupus Erythematosus and its correlation with disease activity: a case control study.Pediatric rheumatology online journal · 2023Article
- Is podocytopathy another image of renal affection in p-SLE?Pediatric rheumatology online journal · 2021Article
- Serum-soluble CXCL16 in juvenile systemic lupus erythematosus: a promising predictor of disease severity and lupus nephritis.Clinical rheumatology · 2018Article
- Urinary interleukin 22 binding protein as a marker of lupus nephritis in Egyptian children with juvenile systemic lupus erythematosus.Clinical rheumatology · 2018Article
- Article
- Taxonomy for systemic lupus erythematosus with onset before adulthood.Arthritis care & research · 2012Review
- Systemic lupus erythematosus in children and adolescents.Pediatric clinics of North America · 2012Review
- Damage index in childhood-onset systemic lupus erythematosus in Egypt.Pediatric rheumatology online journal · 2011Article
- Clinical presentations and outcomes of Filipino juvenile systemic lupus erythematosus.Pediatric rheumatology online journal · 2011Article
- Urinary Neutrophil Gelatinase-Associated Lipocalin and Urinary Soluble CXCL16 as Biomarkers of Activity in Pediatric Lupus Nephritis.Indian journal of nephrologyArticle
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The aim of the study was to study the characteristics of systemic lupus erythematosus (SLE) in the Egyptian population, comparing it to other populations. We retrospectively studied 207 patients with SLE diagnosed between 1990 and 2005. We obtained clinical features and laboratory data and analyzed them statistically. We studied 151 female and 56 male SLE patients. The female to male ratio was 2.7 to 1 and the mean age at presentation was 10 +/- 2.7 years (range 2-16). The mean disease duration was 6.47 +/- 3.74 years. At diagnosis, musculoskeletal, constitutional and mucocutaneous manifestations were the commonest features. During follow-up, the prevalence of nephritis (67%), hematological manifestations (44.9%), photosensitivity (44%), arthritis (39%), malar rash (38.2%), serositis (32.9%) and neuropsychiatric manifestations (24.25%) increased significantly. Those whose age of onset of the disease was <or=5 years (nine patients) had significantly more common hematological affection (P value = 0.0005). The characteristics of SLE in Egyptian patients show some similarities to other series of Middle Eastern countries, but with a lower female to male ratio. Disease onset below 5 years is extremely rare (4.35%), commonly presenting with hematological manifestations. The kidney was the commonest major internal organ involved, and also an important cause of death.
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Registered trials
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