Evidence map›Paper›PMID 19300955›Full record

ReviewJournal of neurology2008

Immunomodulatory treatment strategies in multiple sclerosis.

Bernd C Kieseier, Heinz Wiendl, Verena I Leussink, Olaf Stüve

Abstract readReview
PubMed Publisher
In one paragraph

Review in Journal of neurology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
3.0field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 30 citations in OpenAlex.

  1. Article
  2. Article
  3. Mycophenolate mofetil in combination with interferon beta-1a in the treatment of relapsing-remitting multiple sclerosis: A preliminary study.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2011
    Article
  4. Article
  5. Review
  6. Article
  7. Is multiple sclerosis a mitochondrial disease?Biochimica et biophysica acta · 2010
    Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Bernd C KieseierDepartment of Neurology, Heinrich-Heine University, Moorenstrasse 5, 40225 Düsseldorf, Germany. bernd.kieseier@uni-duesseldorf.de
Heinz Wiendl
Verena I Leussink
Olaf Stüve
Heinrich Heine University Düsseldorf · DEThe University of Texas Southwestern Medical Center · USUniversity of Würzburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Multiple sclerosis (MS) represents the prototypic inflammatory autoimmune disorder of the central nervous system and the most common cause of neurological disability in young adults. The mainstays in the immunomodulatory therapy of MS are currently interferon beta and glatiramer acetate, both of which have proven to be clinically and paraclinically effective. Current clinical evidence indicates that treatment should be initiated as early as possible. In this review we summarize available data from clinical studies on clinical efficacy of immunomodulatory drugs for treating patients with multiple sclerosis.

Indexed as

AnimalsClinical Trials as TopicHumansImmunologic FactorsMultiple SclerosisImmunologic Factors

Identifiers

PMID19300955
OpenAlexW2024636630

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.