Evidence map›Paper›PMID 19300614›Full record

ArticleNeuropsychiatric disease and treatment2007

Neurologic uses of botulinum neurotoxin type A.

John P Ney, Kevin R Joseph

Abstract read
In one paragraph

Article in Neuropsychiatric disease and treatment, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Trial
  4. Pharmaceuticals (Basel, Switzerland) · 2024
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. AbobotulinumtoxinA: A 25-Year History.Aesthetic surgery journal · 2017
    Review
  11. Review
  12. New Uses of AbobotulinumtoxinA in Aesthetics.Aesthetic surgery journal · 2017
    Review
  13. Article
  14. Article
  15. Review
  16. Article
  17. Spasticity mechanisms - for the clinician.Frontiers in neurology · 2010
    Article
  18. Botulinum toxin - From WMD to therapeutic agent and cosmetic aid.Neuropsychiatric disease and treatment · 2007
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

John P NeyMadigan Army Medical Center, Neurology Service, Tacoma, WA, USA.
Kevin R Joseph

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This article reviews the current and most neurologic uses of botulinum neurotoxin type A (BoNT-A), beginning with relevant historical data, neurochemical mechanism at the neuromuscular junction. Current commercial preparations of BoNT-A are reviewed, as are immunologic issues relating to secondary failure of BoNT-A therapy. Clinical uses are summarized with an emphasis on controlled clinical trials (as appropriate), including facial movement disorders, focal neck and limb dystonias, spasticity, hypersecretory syndromes, and pain.

Indexed as

BOTOX®botulinum neurotoxinschemodenervationDysport®

Identifiers

PMID19300614
PMCPMC2656321

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.