ArticlePLoS genetics2009
Independent S-locus mutations caused self-fertility in Arabidopsis thaliana.
Article in PLoS genetics, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers.
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Who cites it
55 citing papers in PubMed, 104 citations in OpenAlex.
- Dominance modifiers at the Arabidopsis self-incompatibility locus retain proto-miRNA features and act through non-canonical pathways.PLoS genetics · 2026Article
- Characterization of long non-coding RNAs during compatible and incompatible pollination inFrontiers in plant science · 2026Article
- Indian Himalayan Arabidopsis thaliana population reflects deep history and might be the source of species expansion in the eastern edge.BMC plant biology · 2025Article
- Insights into the Molecular Basis of Pollen Coat Development and Its Role in Male Sterility.International journal of molecular sciences · 2025Review
- Genomic implications of the repeated shift to self-fertilization across a species' geographic distribution.The Journal of heredity · 2025Article
- Investigating a role for PUB17 and PUB16 in the self-incompatibility signaling pathway in transgenicPlant direct · 2024Article
- A pollen selection system links self and interspecific incompatibility in the Brassicaceae.Nature ecology & evolution · 2024Article
- Stop and go signals at the stigma-pollen interface of the Brassicaceae.Plant physiology · 2023Article
- Transition to Self-compatibility Associated With Dominant S-allele in a Diploid Siberian Progenitor of Allotetraploid Arabidopsis kamchatica Revealed by Arabidopsis lyrata Genomes.Molecular biology and evolution · 2023Article
- Breakdown of self-incompatibility due to genetic interaction between a specific S-allele and an unlinked modifier.Nature communications · 2023Article
- Comprehensive computational analysis of the SRK-SP11 molecular interaction underlying self-incompatibility in Brassicaceae using improved structure prediction for cysteine-rich proteins.Computational and structural biotechnology journal · 2023Article
- Autophagy is required for self-incompatible pollen rejection in two transgenic Arabidopsis thaliana accessions.Plant physiology · 2022Article
- Peptides/receptors signaling during plant fertilization.Frontiers in plant science · 2022Review
- Evolution of self-incompatibility in the Brassicaceae: Lessons from a textbook example of natural selection.Evolutionary applications · 2020Article
- Population Genomics of Transitions to Selfing in Brassicaceae Model Systems.Methods in molecular biology (Clifton, N.J.) · 2020Article
- Double-Locking Mechanism of Self-Compatibility inFrontiers in plant science · 2020Article
- Generation of Transgenic Self-IncompatiblePlants (Basel, Switzerland) · 2019Article
- High temperature causes breakdown of S haplotype-dependent stigmatic self-incompatibility in self-incompatible Arabidopsis thaliana.Journal of experimental botany · 2019Article
- Genome ofProceedings of the National Academy of Sciences of the United States of America · 2019Article
- Review
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A common yet poorly understood evolutionary transition among flowering plants is a switch from outbreeding to an inbreeding mode of mating. The model plant Arabidopsis thaliana evolved to an inbreeding state through the loss of self-incompatibility, a pollen-rejection system in which pollen recognition by the stigma is determined by tightly linked and co-evolving alleles of the S-locus receptor kinase (SRK) and its S-locus cysteine-rich ligand (SCR). Transformation of A. thaliana, with a functional AlSRKb-SCRb gene pair from its outcrossing relative A. lyrata, demonstrated that A. thaliana accessions harbor different sets of cryptic self-fertility-promoting mutations, not only in S-locus genes, but also in other loci required for self-incompatibility. However, it is still not known how many times and in what manner the switch to self-fertility occurred in the A. thaliana lineage. Here, we report on our identification of four accessions that are reverted to full self-incompatibility by transformation with AlSRKb-SCRb, bringing to five the number of accessions in which self-fertility is due to, and was likely caused by, S-locus inactivation. Analysis of S-haplotype organization reveals that inter-haplotypic recombination events, rearrangements, and deletions have restructured the S locus and its genes in these accessions. We also perform a Quantitative Trait Loci (QTL) analysis to identify modifier loci associated with self-fertility in the Col-0 reference accession, which cannot be reverted to full self-incompatibility. Our results indicate that the transition to inbreeding occurred by at least two, and possibly more, independent S-locus mutations, and identify a novel unstable modifier locus that contributes to self-fertility in Col-0.
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