ArticleGenes & development2009
Alternative Ac/Ds transposition induces major chromosomal rearrangements in maize.
Article in Genes & development, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
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Who cites it
34 citing papers in PubMed, 69 citations in OpenAlex.
- Ancient but dynamic: structural expansion, massive gene duplication, and transposable element colonization in a supergene controlling ant social organization.Molecular biology and evolution · 2026Article
- Long-read detection of transposable element mobilization in the soma of hypomethylated Arabidopsis thaliana individuals.Genome biology · 2025Article
- Article
- Rates and spectra of de novo structural mutations inGenome research · 2023Article
- Current strategies employed in the manipulation of gene expression for clinical purposes.Journal of translational medicine · 2022Review
- Excision and reinsertion of Ac macrotransposons in maize.Genetics · 2022Article
- Article
- Ectopic Expression of a Maize Gene Is Induced by Composite Insertions Generated Through Alternative Transposition.Genetics · 2020Article
- Transposon-mediated telomere destabilization: a driver of genome evolution in the blast fungus.Nucleic acids research · 2020Article
- Small RNA-MediatedGenetics · 2020Article
- Genomic Plasticity Mediated by Transposable Elements in the Plant Pathogenic Fungus Colletotrichum higginsianum.Genome biology and evolution · 2019Article
- Whole-chromosome paints in maize reveal rearrangements, nuclear domains, and chromosomal relationships.Proceedings of the National Academy of Sciences of the United States of America · 2019Article
- Review
- Maize Transposon Storm Kicks up aGenetics · 2017Article
- Alternative Transposition Generates New Chimeric Genes and Segmental Duplications at the Maize p1 Locus.Genetics · 2015Article
- Identification and characterization of expressed retrotransposons in the genome of the Paracoccidioides species complex.BMC genomics · 2015Article
- Article
- Generation of tandem direct duplications by reversed-ends transposition of maize ac elements.PLoS genetics · 2013Article
- Transposable elements: powerful contributors to angiosperm evolution and diversity.Genome biology and evolution · 2013Article
- A transgenic system for generation of transposon Ac/Ds-induced chromosome rearrangements in rice.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2012Article
Corrections and comments
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Authors and funding
8 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Barbara McClintock reported that the Ac/Ds transposable element system can generate major chromosomal rearrangements (MCRs), but the underlying mechanism has not been determined. Here, we identified a series of chromosome rearrangements derived from maize lines containing pairs of closely linked Ac transposable element termini. Molecular and cytogenetic analyses showed that the MCRs in these lines comprised 17 reciprocal translocations and two large inversions. The breakpoints of all 19 MCRs are delineated by Ac termini and characteristic 8-base-pair target site duplications, indicating that the MCRs were generated by precise transposition reactions involving the Ac termini of two closely linked elements. This alternative transposition mechanism may have contributed to chromosome evolution and may also occur during V(D)J recombination resulting in oncogenic translocations.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.