Evidence map›Paper›PMID 19299133›Full record

ArticleTrends in microbiology2009

Vesicular transport across the fungal cell wall.

Arturo Casadevall, Joshua D Nosanchuk, Peter Williamson, Marcio L Rodrigues

Abstract read
In one paragraph

Article in Trends in microbiology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 82 papers.

0numbers the graph read from it
0cells of the map it votes in
82citing papers in PubMed
7.6field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

82 citing papers in PubMed, 171 citations in OpenAlex.

  1. Article
  2. Extracellular Vesicles fromJournal of fungi (Basel, Switzerland) · 2026
    Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. Review
  8. Article
  9. Review
  10. Review
  11. The Expanding Mycovirome ofJournal of fungi (Basel, Switzerland) · 2024
    Review
  12. Article
  13. Review
  14. Review
  15. Article
  16. Review
  17. Article
  18. Architecture of the dynamic fungal cell wall.Nature reviews. Microbiology · 2023
    Review
  19. Article
  20. Review

22 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Arturo CasadevallDepartments of Microbiology and Immunology, Department of Medicine, Albert Einstein College of Medicine, Bronx, NY 10461, USA. casadeva@aecom.yu.edu
Joshua D Nosanchuk
Peter Williamson
Marcio L Rodrigues
Albert Einstein College of Medicine · USUniversidade Federal do Rio de Janeiro · BRUniversity of Illinois Chicago · US

Funding

Synergy of Host Defense Mechanisms in the LungR01HL059842 · NHLBI · YESHIVA UNIVERSITY · PI CASADEVALL, ARTURO · 1997 to 2023
$7.4M
Biology of Fungal MelaninR01AI052733 · NIAID · YESHIVA UNIVERSITY · PI CASADEVALL, ARTURO · 2003 to 2019
$6.6M
PROTECTIVE ANTIBODIES FOR CRYPTOCOCCAL INFECTIONSR01AI033774 · NIAID · YESHIVA UNIVERSITY · PI CASADEVALL, ARTURO · 1994 to 2014
$5.6M
Molecular Characterization of C. neoformans AntibodiesR37AI033142 · NIAID · JOHNS HOPKINS UNIVERSITY · PI CASADEVALL, ARTURO · 2007 to 2016
$3.9M
The Role of Unc119 in T Cell Antigen Receptor Signaling1R01AI045995 · NIAID · UNIVERSITY OF ILLINOIS AT CHICAGO · PI COOK, JAMES LOWELL · 1999 to 2009
$2.6M
Antibody Protection in HistoplamosisR01AI056070 · NIAID · ALBERT EINSTEIN COL OF MED YESHIVA UNIV · PI NOSANCHUK, JOSHUA D · 2005 to 2009
$1.8M
MOLECULAR CHARACTERIZATION OF C NEOFORMANS ANTIBODIESR01AI033142 · NIAID · YESHIVA UNIVERSITY · PI CASADEVALL, ARTURO · 1994 to 2006
$1.7M
Virulence Factor Trafficking in CryptococcusR01AI049371 · NIAID · UNIVERSITY OF ILLINOIS AT CHICAGO · PI WILLIAMSON, PETER RICHARD · 2002 to 2005
$1.2M
NHLBI NIH HHS HL059842NHLBI NIH HHS R01 HL059842NIAID NIH HHS AI033142NIAID NIH HHS AI033774NIAID NIH HHS AI056070-01A2NIAID NIH HHS AI45995NIAID NIH HHS AI49371NIAID NIH HHS AI52733NIAID NIH HHS R01 AI033142NIAID NIH HHS R01 AI033774NIAID NIH HHS R01 AI045995NIAID NIH HHS R01 AI049371NIAID NIH HHS R01 AI052733NIAID NIH HHS R01 AI056070NIAID NIH HHS R37 AI033142
6 · The paper itself

Abstract

Recent findings indicate that fungi use vesicular transport to deliver substances across their cell walls. Fungal vesicles are similar to mammalian exosomes and could originate from cytoplasmic multivesicular bodies. Vesicular transport enables the export of large molecules across the cell wall, and vesicles contain lipids, proteins and polysaccharides, many of which are associated with virulence. Concentration of fungal products in vesicles could increase their efficiency in food acquisition and/or delivering potentially noxious substances to other cells, such as amoebae or phagocytes. The discovery of vesicular transport in fungi opens many new avenues for investigation in basic cell biology and pathogenesis.

Indexed as

Biological TransportCell WallFungiPorosityTransport Vesicles

Identifiers

PMID19299133
PMCPMC4282776
OpenAlexW2108316682

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.