Trial reportAddiction biology2009
Do genetic and individual risk factors moderate the efficacy of motivational enhancement therapy? Drinking outcomes with an emerging adult sample.
Trial report in Addiction biology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
36 citing papers in PubMed, 5 syntheses or guidelines pooled it, 53 citations in OpenAlex.
- A systematic review of gene-by-intervention studies of alcohol and other substance use.Development and psychopathology · 2021Pooled it
- Motivational interviewing for the prevention of alcohol misuse in young adults.The Cochrane database of systematic reviews · 2016Pooled it
- Single-Session Alcohol Interventions for Heavy Drinking College Students: A Systematic Review and Meta-Analysis.Journal of studies on alcohol and drugs · 2015Pooled it
- Brief alcohol interventions for adolescents and young adults: a systematic review and meta-analysis.Journal of substance abuse treatment · 2015Pooled it
- The impact of elevated posttraumatic stress on the efficacy of brief alcohol interventions for heavy drinking college students.Addictive behaviors · 2013Pooled it
- Examining executive functioning: A randomized controlled trial of alcohol misuse interventions for college students with attention-deficit/hyperactivity disorder.Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2026Trial
- A pilot trial of a brief intervention for cannabis use supplemented with a substance-free activity session or relaxation training.Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2024Trial
- Motivational interviewing plus behavioral activation for alcohol misuse in college students with ADHD.Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2021Trial
- Enhanced Brief Motivational Intervention for College Student Drinkers With ADHD: Goal-Directed Activation as a Mechanism of Change.Behavior therapy · 2021Trial
- Genetics moderate alcohol and intimate partner violence treatment outcomes in a randomized controlled trial of hazardous drinking men in batterer intervention programs: A preliminary investigation.Journal of consulting and clinical psychology · 2016Trial
- Behavioral economic predictors of brief alcohol intervention outcomes.Journal of consulting and clinical psychology · 2015Trial
- Colorado stride (COSTRIDE): testing genetic and physiological moderators of response to an intervention to increase physical activity.The international journal of behavioral nutrition and physical activity · 2013Trial
- Addressing alcohol use and problems in mandated college students: a randomized clinical trial using stepped care.Journal of consulting and clinical psychology · 2012Trial
- A randomized controlled trial of a behavioral economic supplement to brief motivational interventions for college drinking.Journal of consulting and clinical psychology · 2012Trial
- Trajectories of adolescent alcohol use after brief treatment in an Emergency Department.Drug and alcohol dependence · 2012Trial
- Neurocognitive performance, alcohol withdrawal, and effects of a combination of flumazenil and gabapentin in alcohol dependence.Alcoholism, clinical and experimental research · 2011Trial
- What makes group MET work? A randomized controlled trial of college student drinkers in mandated alcohol diversion.Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2009Trial
- Understanding the interplay of social context and physiology on psychological outcomes in trauma-exposed adolescents: a protocol and baseline data report.European journal of psychotraumatology · 2026Article
- Article
- Adolescents hospitalised for suicidality: biomarkers, social and affective predictors: a cohort study.BMJ open · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
Research indicates that motivational enhancement therapy (MET) helps catalyze reductions in problem drinking among emerging adults. However, moderators of this intervention remain relatively unknown. Therefore, the objectives of this study were: (1) to test whether a single session of MET increased motivation to reduce drinking and drinking outcomes; and (2) to examine whether genetic dopamine D(4) receptor L (DRD4 L) and individual personality risk factors (impulsivity and novelty seeking) moderated the effects of the MET. These hypotheses were evaluated by randomly assigning a sample of emerging adult problem drinkers (n = 67) to receive a single session of MET or alcohol education. Follow-up data indicated that only individuals who were low in impulsivity, novelty seeking and/or who had the short DRD4 variable number of tandem repeats genotype evidenced differentially increased behavior change (taking steps toward reducing drinking) following the MET.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.