ArticleThe American journal of clinical nutrition2009
Size at birth, weight gain in infancy and childhood, and adult blood pressure in 5 low- and middle-income-country cohorts: when does weight gain matter?
Article in The American journal of clinical nutrition, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 88 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
88 citing papers in PubMed, 1 synthesis or guideline pooled it, 168 citations in OpenAlex.
- Is birth weight associated with blood pressure among African children and adolescents? A systematic review.Journal of developmental origins of health and disease · 2018Pooled it
- Growth During Infancy and Early Childhood and Its Association With Metabolic Risk Biomarkers at 11.5 Years of Age.American journal of epidemiology · 2020Trial
- Infant Nutritional Status and Markers of Environmental Enteric Dysfunction are Associated with Midchildhood Anthropometry and Blood Pressure in Tanzania.The Journal of pediatrics · 2017Trial
- Blood pressure and the capacity-load model in 8-year-old children from Nepal: Testing the contributions of kidney size and intergenerational effects.American journal of human biology : the official journal of the Human Biology Council · 2016Trial
- Is infant weight associated with childhood blood pressure? Analysis of the Promotion of Breastfeeding Intervention Trial (PROBIT) cohort.International journal of epidemiology · 2011Trial
- Associations of growth trajectories from birth to two years of age with adolescent blood pressure: the mediating role of current BMI in the follow-up of an antenatal micronutrient supplementation trial.European journal of pediatrics · 2026Observational
- Four methods to identify sensitive periods of infant weight gain associated with adolescent BMI in a Chinese birth cohort.Scientific reports · 2025Observational
- Precision medicine to identify, prevent, and treat pediatric obesity.Pharmacotherapy · 2024Review
- Women's health and well-being in five birth cohorts from low- and middle-income countries: Domains and their associations with early-life conditions.Journal of global health · 2024Article
- The effects of initial and subsequent overweight or obesity on hypertension in the middle age.Journal of clinical hypertension (Greenwich, Conn.) · 2024Article
- Child Development Card (KKA) as a discriminant tool for the growth and development of stunted and normal children in Indonesia.Journal of public health research · 2024Article
- Growth in Infancy and Childhood and Age at Menarche in Five Low- or Middle-Income Countries: Consortium of Health Orientated Research in Transitional Societies (COHORTS).The Journal of nutrition · 2023Article
- Article
- Association between Intestinal Parasite Infections and Proxies for Body Composition: A Scoping Review.Nutrients · 2022Article
- Changes in Body Size during Early Growth Are Independently Associated with Arterial Properties in Early Childhood.Journal of cardiovascular development and disease · 2021Article
- Effect of Correcting the Postnatal Age of Preterm-Born Children on Measures of Associations Between Infant Length-for-Age z Scores and Mid-Childhood Outcomes.American journal of epidemiology · 2021Article
- The associations of low birth weight with primary hypertension in later life: A systematic review and meta-analysis.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2021Review
- Article
- Water, food, and the dual burden of disease in Galápagos, Ecuador.American journal of human biology : the official journal of the Human Biology Council · 2020Article
- Early life growth and adult telomere length in a Filipino cohort study.American journal of human biology : the official journal of the Human Biology Council · 2019Article
28 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors at 8 institutions in 5 countries.
Funding
Abstract
backgroundPromoting catch-up growth in malnourished children has health benefits, but recent evidence suggests that accelerated child weight gain increases adult chronic disease risk.
objectiveWe aimed to determine how birth weight (BW) and weight gain to midchildhood relate to blood pressure (BP) in young adults.
designWe pooled data from birth cohorts in Brazil, Guatemala, India, the Philippines, and South Africa. We used conditional weight (CW), a residual of current weight regressed on prior weights, to represent deviations from expected weight gain from 0 to 12, 12 to 24, 24 to 48 mo, and 48 mo to adulthood. Adult BP and risk of prehypertension or hypertension (P/HTN) were modeled before and after adjustment for adult body mass index (BMI) and height. Interactions of CWs with small size-for-gestational age (SGA) at birth were tested.
resultsHigher CWs were associated with increased BP and odds of P/HTN, with coefficients proportional to the contribution of each CW to adult BMI. Adjusted for adult height and BMI, no child CW was associated with adult BP, but 1 SD of BW was related to a 0.5-mm Hg lower systolic BP and a 9% lower odds of P/HTN. BW and CW associations with systolic BP and P/HTN were not different between adults born SGA and those with normal BW, but higher CW at 48 mo was associated with higher diastolic BP in those born SGA.
conclusionsGreater weight gain at any age relates to elevated adult BP, but faster weight gains in infancy and young childhood do not pose a higher risk than do gains at other ages.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.