ReviewNature immunology2009
Integration of cytokine and heterologous receptor signaling pathways.
Review in Nature immunology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 58 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
58 citing papers in PubMed, 94 citations in OpenAlex.
- The language of the immune system: Part 1: Cytokine conversations and conversationalists.ImmunoHorizons · 2026Review
- Tuning of G-CSFR signaling by de novo-designed agonists.Molecular therapy : the journal of the American Society of Gene Therapy · 2025Article
- Inflammasomes as regulators of mechano-immunity.EMBO reports · 2024Review
- The interweaved signatures of common-gamma-chain cytokines across immunologic lineages.The Journal of experimental medicine · 2023Article
- [Colorectal cancer cells induce the formation of cancer-associated fibroblasts by activating the ERK signaling pathway in fibroblasts].Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2023Article
- The ion channel CALHM6 controls bacterial infection-induced cellular cross-talk at the immunological synapse.The EMBO journal · 2023Article
- NF-kB in Signaling Patterns and Its Temporal Dynamics Encode/Decode Human Diseases.Life (Basel, Switzerland) · 2022Review
- Inflammatory Cytokines That Enhance Antigen Responsiveness of Naïve CD8International journal of molecular sciences · 2022Article
- Bortezomib-containing regiment in treating glomerulopathy with fibronectin deposits combined with monoclonal gammopathy of undetermined significance: a case report and literature review.Annals of translational medicine · 2022Article
- A digital single-molecule nanopillar SERS platform for predicting and monitoring immune toxicities in immunotherapy.Nature communications · 2021Article
- S100A8/S100A9 cytokine acts as a transcriptional coactivator during breast cellular transformation.Science advances · 2021Article
- Unique Molecular Characteristics of Visceral Afferents Arising from Different Levels of the Neuraxis: Location of Afferent Somata Predicts Function and Stimulus Detection Modalities.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2020Article
- A Pilot Study Using a Multistaged Integrated Analysis of Gene Expression and Methylation to Evaluate Mechanisms for Evening Fatigue in Women Who Received Chemotherapy for Breast Cancer.Biological research for nursing · 2019Article
- Research progress in cytokines with chemokine-like function.Cellular & molecular immunology · 2018Review
- Plac1 Is a Key Regulator of the Inflammatory Response and Immune Tolerance In Mammary Tumorigenesis.Scientific reports · 2018Article
- Interferon-γ is a master checkpoint regulator of cytokine-induced differentiation.Proceedings of the National Academy of Sciences of the United States of America · 2017Article
- Synaptoimmunology - roles in health and disease.Molecular brain · 2017Review
- Nectin-4 co-stimulates the prolactin receptor by interacting with SOCS1 and inhibiting its activity on the JAK2-STAT5a signaling pathway.The Journal of biological chemistry · 2017Article
- Targeting microRNAs as key modulators of tumor immune response.Journal of experimental & clinical cancer research : CR · 2016Review
- Article
Corrections and comments
- Erratum issued
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Cytokines are soluble mediators of cell communication that are critical in immune regulation. They induce specific gene-expression programs in responsive cells. Recent findings, however, indicate that cytokine receptors can regulate immune cell functions by transcription-independent mechanisms. Here we review the current understanding of how cytokine signaling regulates the functions of other signaling pathways by first discussing the 'traditional' transcription-mediated consequences of cytokine signaling and then providing a detailed description of transcription-independent lateral communications between cytokine receptors and other cellular receptors.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.