ReviewComparative medicine2009
Effects of Helicobacter infection on research: the case for eradication of Helicobacter from rodent research colonies.
Review in Comparative medicine, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 40 citations in OpenAlex.
- Eradication of Helicobacter spp. by using medicated diet in mice deficient in functional natural killer cells and complement factor D.Journal of the American Association for Laboratory Animal Science : JAALAS · 2010Trial
- Human milk-derived Bifidobacterium longum subsp. infantis CCFM1269 alleviates food allergy by modulating gut microbiota and restoring intestinal barrier.Scientific reports · 2026Article
- Rodent Pathogen Detection via Testing of Soiled Nesting Material.Journal of the American Association for Laboratory Animal Science : JAALAS · 2025Article
- Effective Eradication of Mouse Norovirus and Helicobacter spp. in Laboratory Mice (Mus musculus) via Iodine Immersion and Cross-Fostering Technique.Journal of the American Association for Laboratory Animal Science : JAALAS · 2025Article
- Evaluation of the Efficacy of Disinfectants in Reducing Contamination of Bacterial and Viral Murine Pathogens on Gloved Hands.Journal of the American Association for Laboratory Animal Science : JAALAS · 2024Article
- Effects of Scallop Mantle Toxin on Intestinal Microflora and Intestinal Barrier Function in Mice.Toxins · 2024Article
- Control ofMicrobiology spectrum · 2023Article
- Disease Animal Models for Cancer Research.Methods in molecular biology (Clifton, N.J.) · 2023Article
- Using Sterile Flocked Swabs as an Alternative Method for Rodent Health Monitoring.Journal of the American Association for Laboratory Animal Science : JAALAS · 2022Article
- Evaluation of Pain and Distress and Therapeutic Interventions for Rectal Prolapse in Mice to Reduce Early Study Removal.Journal of the American Association for Laboratory Animal Science : JAALAS · 2021Article
- Comparing Mouse Health Monitoring Between Soiled-bedding Sentinel and Exhaust Air Dust Surveillance Programs.Journal of the American Association for Laboratory Animal Science : JAALAS · 2020Article
- Variations in hepatic lipid species of age-matched male mice fed a methionine-choline-deficient diet and housed in different animal facilities.Lipids in health and disease · 2019Article
- Environmental factors regulate Paneth cell phenotype and host susceptibility to intestinal inflammation in Irgm1-deficient mice.Disease models & mechanisms · 2018Article
- Article
- The role of the IACUC in ensuring research reproducibility.Lab animal · 2017Review
- Association of Helicobacter Pylori Infection and Ectopic Pregnancy.Journal of family & reproductive health · 2016Article
- Metagenomic Analysis of Antibiotic-Induced Changes in Gut Microbiota in a Pregnant Rat Model.Frontiers in pharmacology · 2016Article
- Use of Neonatal Fostering To Remove Helicobacter spp. from Deer Mice (Peromyscus maniculatus).Journal of the American Association for Laboratory Animal Science : JAALAS · 2015Article
- Helicobacter hepaticus infection promotes hepatitis and preneoplastic foci in farnesoid X receptor (FXR) deficient mice.PloS one · 2014Article
- Helicobacter hepaticus increases intestinal injury in a rat model of necrotizing enterocolitis.American journal of physiology. Gastrointestinal and liver physiology · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Infection of mouse colonies with Helicobacter spp. has become an increasing concern for the research community. Although Helicobacter infection may cause clinical disease, investigators may be unaware that their laboratory mice are infected because the pathology of Helicobacter species is host-dependent and may not be recognized clinically. The effects of Helicobacter infections are not limited to the gastrointestinal system and can affect reproduction, the development of cancers in gastrointestinal organs and remote organs such as the breast, responses to vaccines, and other areas of research. The data we present in this review show clearly that unintentional Helicobacter infection has the potential to significantly interfere with the reliability of research studies based on murine models. Therefore, frequent screening of rodent research colonies for Helicobacter spp. and the eradication of these pathogens should be key goals of the research community.
Indexed as
Identifiers
19295050PMC2703140W34814839What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.