ReviewClinical rheumatology2009
Discovertebral (Andersson) lesions of the spine in ankylosing spondylitis revisited.
Review in Clinical rheumatology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 56 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
56 citing papers in PubMed, 1 synthesis or guideline pooled it, 142 citations in OpenAlex.
- 2010 update of the ASAS/EULAR recommendations for the management of ankylosing spondylitis.Annals of the rheumatic diseases · 2011Pooled it
- Deep learning-based synthetic CT for the assessment of spinal structural lesions in axial spondyloarthritis.Skeletal radiology · 2026Article
- Management of a Severe L4/5 Andersson Lesion with Three-Column Instability in Ankylosing Spondylitis Using Single-Stage Circumferential Reconstruction: A Case Report.Journal of clinical medicine · 2026Article
- Andersson-like lesion in diffuse idiopathic skeletal hyperostosis; a rare diagnostic and therapeutic challenge.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026Article
- Infectious Spondylodiscitis of Bacterial Causes in Adults: Epidemiology, Pathophysiology, Diagnostic and Treatment Challenges.Microorganisms · 2026Review
- Surgical algorithms for ankylosing spondylitis-related pseudarthrosis : adapting to radiological and clinical variations.Bone & joint open · 2026Article
- Review of the updated definitions and concepts of spinal lesions in axial spondyloarthritis.Skeletal radiology · 2025Review
- Surgical treatment of ankylosing spondylitis with Andersson lesion in the thoracic spine: a case report and review of the literature.Journal of surgical case reports · 2025Article
- Diagnostic imaging confusion in infectious spondylitis.Journal of orthopaedic surgery and research · 2025Review
- Case Report: Endoscopic lumbar interbody fusion using percutaneous unilateral biportal endoscopy and 3D printing for an andersson lesion in ankylosing spondylitis.Frontiers in surgery · 2025Article
- Decoding the inflammatory-osteogenic axis in ankylosing spondylitis: mechanisms, dysregulation, and emerging therapeutic interventions.Frontiers in immunology · 2025Review
- Lower cervical C6/C7 andersson lesion with upper cervical C1/C2 fracture in ankylosing spondylitis: a case report and literature review.Frontiers in surgery · 2025Article
- Spondylodiscitis and Its Mimickers: A Pictorial Review.Biomedicines · 2024Review
- Detection Ewingella americana from a patient with Andersson lesion in ankylosing spondylitis by metagenomic next-generation sequencing test: a case report.BMC musculoskeletal disorders · 2024Article
- Imaging of Spondylodiscitis: A Comprehensive Updated Review-Multimodality Imaging Findings, Differential Diagnosis, and Specific Microorganisms Detection.Microorganisms · 2024Review
- Unmasking the great imitators-noninfectious conditions masquerading as spinal tuberculosis in a developing country: A single-center case series analysis.North American Spine Society journal · 2023Article
- Spinal Involvement in Patients with Chronic Non-Bacterial Osteomyelitis (CNO): An Analysis of Distinctive Imaging Features.Journal of clinical medicine · 2023Article
- Treating thoracic-lumbar Andersson lesion in patients with ankylosing spondylitis: case series.Annals of medicine and surgery (2012) · 2023Article
- Surgical Treatment of Andersson Lesion of the Lumbar Spine with Minimal Invasion: A Case Report.Orthopaedic surgery · 2022Article
- Treatment of ankylosing spondylitis complicated with a thoracolumbar Andersson lesion by posterior closed osteotomy, debridement and fusion through the fracture line.BMC musculoskeletal disorders · 2022Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A well-known complication in patients with ankylosing spondylitis (AS) is the development of localised vertebral or discovertebral lesions of the spine, which was first described by Andersson in 1937. Since then, many different terms are used in literature to refer to these localised lesions of the spine, including the eponym 'Andersson lesion' (AL). The use of different terms reflects an ongoing debate on the exact aetiology of the AL. In the current study, we performed an extensive review of the literature in order to align communication on aetiology, diagnosis and management between treating physicians. AL may result from inflammation or (stress-) fractures of the complete ankylosed spine. There is no evidence for an infectious origin. Regardless of the exact aetiology, a final common pathway exists, in which mechanical stresses prevent the lesion from fusion and provoke the development of pseudarthrosis. The diagnosis of AL is established on conventional radiography, but computed tomography and magnetic resonance imaging both provide additional information. There is no indication for a diagnostic biopsy. Surgical instrumentation and fusion is considered the principle management in symptomatic AL that fails to resolve from a conservative treatment. We advise to use the term Andersson lesion for these spinal lesions in patients with AS.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.