ArticleClinical research in cardiology : official journal of the German Cardiac Society2009
Chronic total coronary occlusions in patients with stable angina pectoris: impact on therapy and outcome in present day clinical practice.
Article in Clinical research in cardiology : official journal of the German Cardiac Society, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 4 registered trials, which are not on this map. Cited by 53 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
SHam-controlled INtErvention to Improve QOL in CTOs: the SHINE CTO Trial
Properties of Myocardial Microcirculation in Patients With Different Pathomorphological Substrates, Before and After Recanalization of Coronary Artery Chronic Total Occlusion
Prospective, Multicentric Observational Study Evaluating the Management of Chronic Coronary Occlusions In France
Drug-coated Balloons Treatment in Chronic Total Occlusion Coronary Artery Disease Guided by Intravascular Ultrasound
Who cites it
53 citing papers in PubMed, 3 syntheses or guidelines pooled it, 134 citations in OpenAlex.
- Comparison of successful versus failed percutaneous coronary intervention in patients with chronic total occlusion: A systematic review and meta-analysis.Cardiology journal · 2024Pooled it
- Impact of impaired renal function on outcomes of chronic total occlusion undergoing revascularization: a systemic review and meta-analysis.International urology and nephrology · 2022Pooled it
- Percutaneous Coronary Intervention Versus Medical Therapy for Chronic Total Occlusion of Coronary Arteries: A Systematic Review and Meta-Analysis.Current atherosclerosis reports · 2019Pooled it
- Percutaneous Coronary Intervention for Chronic Total Occlusion in Single Coronary Arteries.Texas Heart Institute journal · 2021Trial
- Music in the cath lab: who should select it?Clinical research in cardiology : official journal of the German Cardiac Society · 2011Trial
- Myocardial Viability and Ischaemia in Chronic Total Occlusion.Medicina (Kaunas, Lithuania) · 2026Article
- QFR measurements post CTO percutaneous coronary intervention: Can the long term outcome be predicted?International journal of cardiology. Heart & vasculature · 2025Article
- Intramyocardial Hematoma After Percutaneous Coronary Intervention for Chronic Total Occlusion: Two Case Reports.Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions · 2025Article
- Future Training Pathways in Percutaneous Coronary Interventions: Interventional Critical Care, Complex Coronary Interventions, and Interventional Heart Failure.JACC. Advances · 2024Review
- Percutaneous Coronary Intervention versus Optimal Medical Therapy in Patients with Chronic Total Occlusion: A Meta-Analysis.Journal of clinical medicine · 2024Review
- Baseline angina burden predicts quality of life and functional improvement in patients with viable myocardium treated for chronic total occlusion.The international journal of cardiovascular imaging · 2023Observational
- Coronary computed tomography angiography and single-photon emission computerized tomography in chronic total occlusions: the Rosetta Stone for PCI planning?Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2023Article
- Predicting Residual Angina After Chronic Total Occlusion Percutaneous Coronary Intervention: Insights from the OPEN-CTO Registry.Journal of the American Heart Association · 2022Article
- A Novel Classification for Predicting Chronic Total Occlusion Percutaneous Coronary Intervention.Frontiers in cardiovascular medicine · 2022Article
- Functional recovery after percutaneous revascularization of coronary chronic total occlusions: insights from cardiac magnetic resonance tissue tracking.The international journal of cardiovascular imaging · 2021Article
- Review
- Trends and outcomes of chronic coronary total occlusion-related ventricular tachyarrhythmias.Proceedings (Baylor University. Medical Center) · 2021Article
- Relationship between quality of coronary collateral and myocardial viability in chronic total occlusion: a magnetic resonance study.The international journal of cardiovascular imaging · 2021Article
- Prognostic impact of coronary chronic total occlusion on recurrences of ventricular tachyarrhythmias and ICD therapies.Clinical research in cardiology : official journal of the German Cardiac Society · 2021Article
- Prognostic Impact of Percutaneous Coronary Intervention of Chronic Total Occlusion in Acute and Periprocedural Myocardial Infarction.Journal of clinical medicine · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundChronic total coronary occlusions (CTOs) represent a subgroup of coronary lesions with a low procedural success and high recurrence rate. However, there is evidence for a prognostic benefit of revascularizing a CTO.
objectiveThis study assessed the prevalence of CTOs among patients with stable angina pectoris and its impact on therapeutic strategies.
methodsBetween 2001 and 2003, a survey was conducted in 64 sites to analyze the outcome of the first diagnostic angiography in patients presenting with stable angina pectoris (STAR registry). The clinical characteristics, initial angiographic findings, therapeutic strategy and outcome within the first year were analyzed.
resultsA total of 2,002 patients were entered into the registry. One-third had at least one CTO. At 1 year, the mortality in patients with a CTO was significantly higher than in those without a CTO (5.5 vs. 3.1%; P = 0.009). This excess mortality was related to a higher prevalence of confounding factors in patients with a CTO such as diabetes and more severe LV dysfunction. Patients with a CTO were more likely to undergo surgery or being treated medically, whereas patients without a CTO were more likely to undergo PCI. If a CTO was treated by PCI the periprocedural and long-term outcome was similar to those with PCI for a non-occlusive lesion. However, periprocedural MACE was higher for patients treated for a non-occlusive lesion without first treating the CTO.
conclusionsThe prevalence of CTOs in patients with stable angina pectoris is high, and it influences the clinical outcome within the first year. The therapeutic strategy is influenced towards a rather conservative approach and lower rates of interventional therapy.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.