Evidence map›Paper›PMID 19293739›Full record

ArticleDisaster medicine and public health preparedness2009

Thermal stress and point-of-care testing performance: suitability of glucose test strips and blood gas cartridges for disaster response.

Richard F Louie, Stephanie L Sumner, Shaunyé Belcher, Ron Mathew, Nam K Tran, Gerald J Kost

Open access · greenAbstract read
In one paragraph

Article in Disaster medicine and public health preparedness, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 40 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Richard F LouieUniversity of California, Davis-Lawrence Livermore National Laboratory Point-of-Care Technologies Center, CA, USA. rflouie@ucdavis.edu
Stephanie L Sumner
Shaunyé Belcher
Ron Mathew
Nam K Tran
Gerald J Kost
University of California, Davis · USLawrence Livermore National Laboratory · US

Funding

Rapid Multipathogen Detection for POCT and National Diaster ReadinessU54EB007959 · NIBIB · UNIVERSITY OF CALIFORNIA AT DAVIS · PI KOST, GERALD JOSEPH · 2007 to 2011
$8.5M
NIBIB NIH HHS U54 EB007959NIBIB NIH HHS U54EB007959
6 · The paper itself

Abstract

objectivePoint-of-care testing (POCT) devices are deployed in the field for emergency on-site testing under a wide range of environmental conditions. Our objective was to evaluate the performance of glucose meter test strips and handheld blood gas analyzer cartridges following thermal stresses that simulate field conditions.

methodsWe evaluated electrochemical and spectrophotometric glucose meter systems and a handheld blood gas analyzer. Glucose test strips were cold-stressed (-21 degrees C) and heat-stressed (40 degrees C) for up to 4 weeks. Blood gas cartridges were stressed at -21 degrees C, 2 degrees C, and 40 degrees C for up to 72 hours. Test strip and cartridge performance was evaluated using aqueous quality control solutions. Results were compared with those obtained with unstressed POCT strips and cartridges.

resultsHeated glucose test strips and blood gas cartridges yielded elevated results. Frozen test strips and cooled cartridges yielded depressed glucose and blood gas results, respectively. Frozen cartridges failed.

conclusionsThe performance of glucose test strips and blood gas cartridges was affected adversely by thermal stresses. Heating generated elevated results, and cooling depressed results. Disaster medical assistance teams and emergency medical responders should be aware of these risks. Field POCT devices must be robust to withstand adverse conditions. We recommend that industry produce POCT devices and reagents suitable for disaster medical assistance teams.

Indexed as

Cold TemperatureDisaster PlanningHot TemperaturePoint-of-Care SystemsBlood Gas AnalysisDiagnostic Tests, RoutineEquipment Failure AnalysisGlucoseGlucose

Identifiers

PMID19293739
PMCPMC2717087
OpenAlexW2061703611

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.