Evidence map›Paper›PMID 19293455›Full record

ArticleILAR journal2009

Gene therapy in large animal models of human genetic diseases. Introduction.

John H Wolfe

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ILAR journal, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Review
  2. Review
  3. Perspectives of pluripotent stem cells in livestock.World journal of stem cells · 2021
    Review
  4. Review
  5. Drug discovery and development for rare genetic disorders.American journal of medical genetics. Part A · 2017
    Review
  6. Review
  7. Review
  8. Precision editing of large animal genomes.Advances in genetics · 2012
    Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

John H WolfeWF Goodman Center for Comparative Medical Genetics at the University of Pennsylvania School of Veterinary Medicine and Stokes Investigator at the Children's Hospital of Philadelphia, PA 19104, USA. jhwolfe@vet.upenn.edu

Funding

INSTITUTIONAL CLINICAL AND TRANSLATIONAL SCIENCE AWARDUL1RR024134 · NCRR · UNIVERSITY OF PENNSYLVANIA · PI FITZGERALD, GARRET A · 2006 to 2011
$70.4M
Vector CoreP30DK047757 · NIDDK · UNIVERSITY OF PENNSYLVANIA · PI WILSON, JAMES M · 1993 to 2017
$18.0M
Gene transfer &NMR studies in alpha-mannosidosis brainR01DK063973 · NIDDK · CHILDREN'S HOSP OF PHILADELPHIA · PI WOLFE, JOHN H · 2002 to 2025
$11.0M
X-LINKED SEVERE COMBINED IMMUNODEFICIENCY IN THE DOGP40RR002512 · NCRR · UNIVERSITY OF PENNSYLVANIA · PI HASKINS, MARK E · 1985 to 2011
$7.6M
Disseminated AAV Vector Transport in the Brain Via Neuronal PathwaysR01NS038690 · NINDS · CHILDREN'S HOSP OF PHILADELPHIA · PI WOLFE, JOHN H · 2000 to 2015
$6.7M
Gene Transfer to Expression in Neurons In vivoR01NS029390 · NINDS · WISTAR INSTITUTE · PI FRASER, NIGEL WILLIAM · 1991 to 2013
$4.3M
Stem Cell Transplantation for Neurogenetic DiseaseR01NS056243 · NINDS · CHILDREN'S HOSP OF PHILADELPHIA · PI WOLFE, JOHN H · 2007 to 2011
$1.9M
NCRR NIH HHS P40 RR002512NCRR NIH HHS UL1 RR024134NIDDK NIH HHS P30 DK047757NIDDK NIH HHS R01 DK063973NINDS NIH HHS R01 NS029390NINDS NIH HHS R01 NS038690NINDS NIH HHS R01 NS056243
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Disease Models, AnimalGene Transfer TechniquesAnimalsGenetic Diseases, InbornGenetic Therapy

Identifiers

PMID19293455
PMCPMC2859173

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.