ArticleProceedings of the National Academy of Sciences of the United States of America2009
Electrophysiological correlates of default-mode processing in macaque posterior cingulate cortex.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 109 papers, 5 of them syntheses that pooled it.
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Who cites it
109 citing papers in PubMed, 5 syntheses or guidelines pooled it.
- Shared and distinct neural activity during anticipation and outcome of win and loss: A meta-analysis of the monetary incentive delay task.NeuroImage · 2022Pooled it
- Toward a cumulative science of functional integration: A meta-analysis of psychophysiological interactions.Human brain mapping · 2016Pooled it
- Subspecialization in the human posterior medial cortex.NeuroImage · 2015Pooled it
- Default mode of brain function in monkeys.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2011Pooled it
- Reading networks at rest.Cerebral cortex (New York, N.Y. : 1991) · 2010Pooled it
- A true response of the brain network during electroacupuncture stimulation at scalp acupoints: An fMRI with simultaneous EAS study.Brain and behavior · 2023Trial
- Cortical Connectivity Moderators of Antidepressant vs Placebo Treatment Response in Major Depressive Disorder: Secondary Analysis of a Randomized Clinical Trial.JAMA psychiatry · 2020Trial
- Neuroimaging findings from an experimental pharmacology trial of naltrexone in heavy drinkers of East Asian descent.Drug and alcohol dependence · 2019Trial
- Spatial and temporal heterogeneity of neural responses in human posteromedial cortex.Proceedings of the National Academy of Sciences of the United States of America · 2018Trial
- NMDA receptor function in large-scale anticorrelated neural systems with implications for cognition and schizophrenia.Proceedings of the National Academy of Sciences of the United States of America · 2012Trial
- Electrophysiological dissociation of human posterior cingulate cortex contributions to value- and memory-based decision-making.bioRxiv : the preprint server for biology · 2026Article
- Reversed functional gradient in primate prefrontal cortex: Posterior dominance and frontopolar task-related deactivation.Science advances · 2026Article
- Task-evoked deactivations: dissociation between BOLD fMRI and FDG.bioRxiv : the preprint server for biology · 2026Article
- The neurovascular impulse response function differentially reflects intrinsic neuromodulation across cortical regions.Nature neuroscience · 2026Article
- Disrupted Coupling Between Cerebral Glucose Metabolism and Intrinsic Functional Connectivity: A Hybrid PET/fMRI Study on Frontotemporal Dementia.Human brain mapping · 2025Article
- Developmental trajectory of neural activity underlying motor control differs by sequence complexity and motor stage.NeuroImage · 2025Article
- Cognitive network interactions through communication subspaces in large-scale models of the neocortex.bioRxiv : the preprint server for biology · 2024Article
- Changes in cortical manifold structure following stroke and its relation to behavioral recovery in the male macaque.Nature communications · 2024Article
- Antagonistic behavior of brain networks mediated by low-frequency oscillations: electrophysiological dynamics during internal-external attention switching.Communications biology · 2024Article
- Mediodorsal thalamus and ventral pallidum contribute to subcortical regulation of the default mode network.Communications biology · 2024Article
49 more citing papers are in PubMed but not listed here.
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3 authors.
Funding
Abstract
During the course of daily activity, our level of engagement with the world varies on a moment-to-moment basis. Although these fluctuations in vigilance have critical consequences for our thoughts and actions, almost nothing is known about the neuronal substrates governing such dynamic variations in task engagement. We investigated the hypothesis that the posterior cingulate cortex (CGp), a region linked to default-mode processing by hemodynamic and metabolic measures, controls such variations. We recorded the activity of single neurons in CGp in 2 macaque monkeys performing simple tasks in which their behavior varied from vigilant to inattentive. We found that firing rates were reliably suppressed during task performance and returned to a higher resting baseline between trials. Importantly, higher firing rates predicted errors and slow behavioral responses, and were also observed during cued rest periods when monkeys were temporarily liberated from exteroceptive vigilance. These patterns of activity were not observed in the lateral intraparietal area, an area linked to the frontoparietal attention network. Our findings provide physiological confirmation that CGp mediates exteroceptive vigilance and are consistent with the idea that CGp is part of the "default network" of brain areas associated with control of task engagement.
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