ArticleThe Plant journal : for cell and molecular biology2009
Peroxule extension over ER-defined paths constitutes a rapid subcellular response to hydroxyl stress.
Article in The Plant journal : for cell and molecular biology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers.
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Who cites it
55 citing papers in PubMed.
- Plant plastids: from evolutionary origins to functional specialization and organelle interactions.Journal of experimental botany · 2025Review
- Peroxisomal-dependent signalling and dynamics modulate plant stress responses: reactive oxygen and nitrogen species as key molecules.Journal of experimental botany · 2025Review
- Peroxisomal homeostasis in metabolic diseases and its implication in ferroptosis.Cell communication and signaling : CCS · 2024Review
- High-content image screening to identify chemical modulators for peroxisome and ferroptosis.Cellular & molecular biology letters · 2024Article
- Using ER-Targeted Photoconvertible Fluorescent Proteins in Living Plant Cells.Methods in molecular biology (Clifton, N.J.) · 2024Article
- Organelle Interactions in Plant Cells.Results and problems in cell differentiation · 2024Review
- Organelle Membrane Extensions in Mammalian Cells.Biology · 2023Review
- Membrane contacts with the endoplasmic reticulum modulate plastid morphology and behaviour.Frontiers in plant science · 2023Article
- Endoplasmic Reticulum Stress and Reactive Oxygen Species in Plants.Antioxidants (Basel, Switzerland) · 2022Review
- A glossary of plant cell structures: Current insights and future questions.The Plant cell · 2022Review
- A high-throughput quantitative method to evaluate peroxisome-chloroplast interactions inFrontiers in plant science · 2022Article
- Heat and drought induced transcriptomic changes in barley varieties with contrasting stress response phenotypes.Frontiers in plant science · 2022Article
- The ER Is a Common Mediator for the Behavior and Interactions of Other Organelles.Frontiers in plant science · 2022Article
- Peroxisomes as redox-signaling nodes in intracellular communication and stress responses.Plant physiology · 2021Review
- Organelle extensions in plant cells.Plant physiology · 2021Article
- Peroxisomal Metabolism and Dynamics at the Crossroads Between Stimulus Perception and Fast Cell Responses to the Environment.Frontiers in cell and developmental biology · 2020Article
- It Started With a Kiss: Monitoring Organelle Interactions and Identifying Membrane Contact Site Components in Plants.Frontiers in plant science · 2020Review
- Peroxisome Plasticity at the Virus-Host Interface.Trends in microbiology · 2019Review
- Multilevel Regulation of Peroxisomal Proteome by Post-Translational Modifications.International journal of molecular sciences · 2019Review
- Selective Autophagy of Peroxisomes in Plants: From Housekeeping to Development and Stress Responses.Frontiers in plant science · 2019Review
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5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Plants survive against myriad environmental odds while remaining rooted to a single spot. The time scale over which plant cells can respond to environmental cues is seldom appreciated. Fluorescent protein-assisted live imaging of peroxisomes reveals that they respond within seconds of exposure to hydrogen peroxide and hydroxyl radicals by producing dynamic extensions called peroxules. Observations of the Arabidopsis flu mutant and treatments with xenobiotics eliciting singlet oxygen and superoxide reactive oxygen species suggest that the observed responses are specific for hydroxyl radicals. Prolonged exposure to hydroxyl radicals inhibits peroxule extension, and instead causes motile and spherical peroxisomes in a cell to become immotile and elongate several-fold. Expression of photo-convertible EosFP-PTS1 demonstrates that vermiform peroxisomes result from rapid stretching of individual peroxisomes, while the subsequent 'beads-on-a-string' morphology results from differential protein distribution within an elongated tubule. Over time, the beads in elongated peroxisomes also extend peroxules randomly before undergoing asynchronous, asymmetrical fission. Peroxule extension does not appear to involve cytoskeletal elements directly, but is closely aligned with and reflects the dynamics of ER tubules. Peroxisomal responses reveal a rapidly invoked subcellular machinery that is involved in recognition of hydroxyl stress thresholds, and its possible remediation locally through extension of peroxules or globally by increasing peroxisome numbers. A matrix protein retro-flow mechanism that supports peroxisome-ER connectivity in plant cells is suggested.
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19292761What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.