Evidence map›Paper›PMID 19292608›Full record

ReviewBreastfeeding medicine : the official journal of the Academy of Breastfeeding Medicine2009

Academy of Breastfeeding Medicine founder's lecture 2008: breastfeeding--an extrauterine link between mother and child.

Samuli Rautava, W Allan Walker

Abstract readReview
In one paragraph

Review in Breastfeeding medicine : the official journal of the Academy of Breastfeeding Medicine, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed.

  1. Trial
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  8. The microbiome in asthma: Role in pathogenesis, phenotype, and response to treatment.Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology · 2019
    Review
  9. Review
  10. Review
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  12. Review
  13. Review
  14. Article
  15. Early Infant Feeding Practices May Influence the Onset of Symptomatic Celiac Disease.Pediatric gastroenterology, hepatology & nutrition · 2016
    Article
  16. Review
  17. Review
  18. Article
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  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Samuli RautavaDevelopmental Gastroenterology Laboratory, Division of Pediatric Gastroenterology, Massachusetts General Hospital for Children, Charlestown, Massachusetts, USA. samrau@utu.fi
W Allan Walker

Funding

ROLE OF DIETARY CONSTITUENTS ON GENE EXPRESSION IN INTESTINAL EPITHELIUMP30DK040561 · NIDDK · MASSACHUSETTS GENERAL HOSPITAL · PI CHRISTOPHER P DUGGAN · 1994 to 2026
$31.6M
EFFECT OF COLOSTRUM ON GUT MATURATION AND HOST DEFENSER01HD012437 · NICHD · MASSACHUSETTS GENERAL HOSPITAL · PI WALKER, W ALLAN · 1989 to 2013
$2.0M
Ontogeny of the intestinal mucosal barrier and NECR01DK070260 · NIDDK · MASSACHUSETTS GENERAL HOSPITAL · PI WALKER, W ALLAN · 2005 to 2009
$1.8M
NICHD NIH HHS R01-HD12437NIDDK NIH HHS P01-DK33560NIDDK NIH HHS P30 DK040561NIDDK NIH HHS P30-DK405610NIDDK NIH HHS R01-DK70260
6 · The paper itself

Abstract

In addition to a near-optimal combination of nutrients for the growing infant, breastmilk contains a wide array of bioactive molecules that are known to protect the infant against infectious disease and modulate the composition of the indigenous intestinal microbiota. A growing number of factors that modulate the infant's immunophysiology have also been identified in breastmilk. We suggest that this early immunomodulation via breastmilk is vital for infant health and may explain the epidemiological data indicating that breastmilk reduces the risk of immunoinflammatory conditions in infancy and also later in life. The body of scientific data regarding the role of transforming growth factor-beta in breastmilk in enhancing healthy immune maturation and reducing the risk of disease is reviewed in this article.

Indexed as

Breast FeedingBacterial Physiological PhenomenaGastrointestinal TractHumansInfantInfant, NewbornInfant Nutritional Physiological PhenomenaMilk, HumanTransforming Growth Factor betaTransforming Growth Factor beta

Identifiers

PMID19292608
PMCPMC2932545

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.