Evidence map›Paper›PMID 19291816›Full record

ReviewWorld journal of gastroenterology2009

In vitro and in vivo models of acute alcohol exposure.

Angela Dolganiuc, Gyongyi Szabo

Abstract readReview
In one paragraph

Review in World journal of gastroenterology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers.

0numbers the graph read from it
0cells of the map it votes in
48citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

48 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Angela DolganiucDepartment of Medicine, University of Massachusetts Medical School, 364 Plantation Street, Worcester, MA 01605, United States. angela.dolganiuc@umassmed.edu
Gyongyi Szabo

Funding

HCV, Alcohol and Host DefenseR37AA014372 · NIAAA · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI SZABO, GYONGYI · 2008 to 2017
$3.7M
Hepatitis C Virus, Alcohol and Host DefenseR01AA014372 · NIAAA · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI SZABO, GYONGYI · 2003 to 2007
$2.0M
Alcohol disrupts TLR4 signaling in lipid raftsR21AA016571 · NIAAA · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI DOLGANIUC, ANGELA · 2007 to 2008
$427k
NIAAA NIH HHS AA014372NIAAA NIH HHS AA016571NIAAA NIH HHS R01 AA014372NIAAA NIH HHS R21 AA016571NIAAA NIH HHS R37 AA014372
6 · The paper itself

Abstract

Alcohol abuse is a global problem due to the financial burden on society and the healthcare system. While the harmful health effects of chronic alcohol abuse are well established, more recent data suggest that acute alcohol consumption also affects human wellbeing. Thus, there is a need for research models in order to fully understand the effect of acute alcohol abuse on different body systems and organs. The present manuscript summarizes the interdisciplinary advantages and disadvantages of currently available human and non-human models of acute alcohol abuse, and identifies their suitability for biomedical research.

Indexed as

Alcohol DrinkingAlcoholismAnimalsBehaviorBehavior, AnimalEthanolHumansInvertebratesMammalsModels, BiologicalPrimatesUnited StatesVertebratesEthanol

Identifiers

PMID19291816
PMCPMC2658858

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.