Evidence map›Paper›PMID 19291708›Full record

ReviewMedicinal research reviews2010

Carbohydrate recognition by boronolectins, small molecules, and lectins.

Shan Jin, Yunfeng Cheng, Suazette Reid, Minyong Li, Binghe Wang

Abstract readReview
In one paragraph

Review in Medicinal research reviews, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 71 papers.

0numbers the graph read from it
0cells of the map it votes in
71citing papers in PubMed
10.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

71 citing papers in PubMed, 302 citations in OpenAlex.

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  16. Synthetic lectins for selective binding of glycoproteins in water.Chemical communications (Cambridge, England) · 2020
    Article
  17. Review
  18. Article
  19. Article
  20. Article

11 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Shan JinDepartment of Chemistry and Center for Biotechnology and Drug Design, Georgia State University, Atlanta, Georgia 30302-4098, USA.
Yunfeng Cheng
Suazette Reid
Minyong Li
Binghe Wang
Georgia State University · US

Funding

Selection of Boronic Acid-modified Aptamers for GlycoproteinsR01GM084933 · NIGMS · GEORGIA STATE UNIVERSITY · PI WANG, BINGHE · 2008 to 2011
$1.2M
Aptamer-based Glycomics ToolsR42GM086925 · NIGMS · ECHELON BIOSCIENCES, INC. · PI WANG, BINGHE · 2009 to 2010
$555k
FLUORESCENT TAGS TARGETED ON CELL SURFACE CARBOHYDRATESR33CA088343 · NCI · NORTH CAROLINA STATE UNIVERSITY RALEIGH · PI WANG, BINGHE · 2002 to 2003
$555k
Fluorescent Aptamers for Glycoprotein DetectionR21CA113917 · NCI · GEORGIA STATE UNIVERSITY · PI WANG, BINGHE · 2005 to 2006
$366k
MRI contrast agents targeting carbohydrate biomarkersR21CA123329 · NCI · GEORGIA STATE UNIVERSITY · PI WANG, BINGHE · 2006 to 2007
$357k
FLUORESCENT TAGS TARGETED ON CELL SURFACE CARBOHYDRATESR21CA088343 · NCI · NORTH CAROLINA STATE UNIVERSITY RALEIGH · PI WANG, BINGHE · 2000 to 2001
$288k
GLUCOSE SENSITIVE ARTIFICIAL RECEPTORS FOR INSULINR21DK055062 · NIDDK · NORTH CAROLINA STATE UNIVERSITY RALEIGH · PI WANG, BINGHE · 1998 to 1999
–
NCI NIH HHS CA113917NCI NIH HHS CA122536NCI NIH HHS CA123329NCI NIH HHS CA88343NCI NIH HHS N01-CO-27184NCI NIH HHS R21 CA088343NCI NIH HHS R21 CA113917NCI NIH HHS R21 CA123329NCI NIH HHS R33 CA088343NIDDK NIH HHS DK55062NIGMS NIH HHS GM084933NIGMS NIH HHS GM086925NIGMS NIH HHS R01 GM084933NIGMS NIH HHS R42 GM086925
6 · The paper itself

Abstract

Carbohydrates are known to mediate a large number of biological and pathological events. Small and macromolecules capable of carbohydrate recognition have great potentials as research tools, diagnostics, vectors for targeted delivery of therapeutic and imaging agents, and therapeutic agents. However, this potential is far from being realized. One key issue is the difficulty in the development of "binders" capable of specific recognition of carbohydrates of biological relevance. This review discusses systematically the general approaches that are available in developing carbohydrate sensors and "binders/receptors," and their applications. The focus is on discoveries during the last 5 years.

Indexed as

AnimalsAntigens, NeoplasmBiomarkers, TumorBoronic AcidsCarbohydratesCattleCell Line, TumorE-SelectinFluorescent DyesHumansKineticsLectinsLigandsMiceProtein BindingAntigens, NeoplasmBiomarkers, TumorBoronic AcidsCarbohydratesE-SelectinFluorescent DyesLectinsLigands

Identifiers

PMID19291708
PMCPMC2829346
OpenAlexW2100014618

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.