ArticleArchives of dermatology2009
Cross-sectional analysis of a collaborative Web-based database for lupus erythematosus-associated skin lesions: prospective enrollment of 114 patients.
Article in Archives of dermatology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
29 citing papers in PubMed, 61 citations in OpenAlex.
- Lenalidomide in treatment-refractory cutaneous lupus erythematosus: Efficacy and safety in a 52-week trial.Journal of the American Academy of Dermatology · 2014Trial
- Characterizing cutaneous manifestations of systemic autoimmune rheumatologic diseases in Filipino skin.International journal of women's dermatology · 2026Article
- Ashes to Rashes: An Exploration of the Intersection Between Smoking and Cutaneous Lupus Erythematosus.Biomolecules · 2025Review
- The Spectrum of Cutaneous Manifestations in Lupus Erythematosus: A Comprehensive Review.Journal of clinical medicine · 2024Review
- Editorial: Cutaneous lupus erythematosus landscape: pathophysiology, unmet needs, and related challenges in clinical practice. What is on the horizon?Frontiers in medicine · 2024Article
- State of current management of the heightened risk for atherosclerotic cardiovascular events in an established cohort of patients with lupus erythematosus.Lupus science & medicine · 2023Article
- Development of a working core outcome set for cutaneous lupus erythematosus: a practical approach to an urgent unmet need.Lupus science & medicine · 2021Review
- The CLASI, a validated tool for the evaluation of skin disease in lupus erythematosus: a narrative review.Annals of translational medicine · 2021Review
- Association of African-American ethnicity and smoking status with total and individual damage index in systemic lupus erythematosus.Clinical rheumatology · 2020Article
- Chronic Cutaneous Lupus Erythematosus: Depression Burden and Associated Factors.American journal of clinical dermatology · 2019Article
- Lupus community panel proposals for optimising clinical trials: 2018.Lupus science & medicine · 2018Review
- Quinacrine Suppresses Tumor Necrosis Factor-α and IFN-α in Dermatomyositis and Cutaneous Lupus Erythematosus.The journal of investigative dermatology. Symposium proceedings · 2017Article
- Characteristics and Alternative Treatment Outcomes of Antimalarial-Refractory Cutaneous Lupus Erythematosus.JAMA dermatology · 2017Article
- The impact of skin damage due to cutaneous lupus on quality of life.The British journal of dermatology · 2014Article
- Cutaneous lupus erythematosus: diagnosis and treatment.Best practice & research. Clinical rheumatology · 2013Review
- Update on Epidemiology and Clinical Assessment Tools of Cutaneous Lupus Erythematosus and Dermatomyositis.Current dermatology reports · 2013Article
- Treatment of Cutaneous Lupus Erythematosus: Review and Assessment of Treatment Benefits Based on Oxford Centre for Evidence-based Medicine Criteria.The Journal of clinical and aesthetic dermatology · 2013Article
- A multicentre, cross-sectional study on quality of life in patients with cutaneous lupus erythematosus.The British journal of dermatology · 2013Article
- New insights into mechanisms of therapeutic effects of antimalarial agents in SLE.Nature reviews. Rheumatology · 2012Review
- The interferon-regulated gene signature is elevated in subacute cutaneous lupus erythematosus and discoid lupus erythematosus and correlates with the cutaneous lupus area and severity index score.The British journal of dermatology · 2012Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
Abstract
objectivesTo assess disease severity in subsets of patients with cutaneous lupus erythematosus (CLE) by using outcome and quality-of-life measures, and to determine treatment responsiveness by establishing a Web-based database of patients with skin manifestations of lupus.
designProspective, cross-sectional study.
settingUniversity hospital cutaneous autoimmunity outpatient clinic. PATIENTS: One hundred fourteen patients who presented from January 15, 2007, to November 8, 2007, and met the criteria for having CLE or lupus-nonspecific skin disease.
main outcome measuresScores on the CLE Disease Activity and Severity Index and the modified Skindex-29 (a quality-of-life measure) completed at each visit.
resultsSeven patients (6.1%) presented with acute CLE, 21 (18.4%) with subacute CLE, 77 (67.5%) with chronic CLE, 7 (6.1%) with systemic lupus erythematosus and LE-nonspecific skin lesions, and 1 (0.9%) with LE-nonspecific skin disease only. The mean baseline CLE Disease Activity and Severity Index activity/damage scores in patients with acute, subacute, and chronic CLE were 6.4/5.1, 11.1/1.6, and 7.5/10.2, respectively. The mean baseline modified Skindex-29 scores were 76.3, 79.4, and 82.7, respectively (P = .80). The disease in 11 of the patients (9.6%) was considered refractory to conventional therapies. Significantly more patients in the refractory group than the nonrefractory group were current smokers (P = .006).
conclusionThis Web-based database should allow collection of data related to disease activity, quality of life, and response to therapy at multiple centers.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.