ArticlePlant molecular biology2009
Overexpression of Arabidopsis damaged DNA binding protein 1A (DDB1A) enhances UV tolerance.
Article in Plant molecular biology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 44 citations in OpenAlex.
- Plant tolerance mechanisms to DNA-damaging UV stress.Journal of experimental botany · 2025Review
- Global repair is the primary nucleotide excision repair subpathway for the removal of pyrimidine-pyrimidone (6-4) damage from the Arabidopsis genome.Scientific reports · 2024Article
- Article
- Genome-Wide Association Study for Ultraviolet-B Resistance in Soybean (Plants (Basel, Switzerland) · 2021Article
- The Dark Side of UV-Induced DNA Lesion Repair.Genes · 2020Review
- Arabidopsis CRL4 Complexes: Surveying Chromatin States and Gene Expression.Frontiers in plant science · 2019Review
- DNA Damage Inducible Protein 1 is Involved in Cold Adaption of Harvested Cucumber Fruit.Frontiers in plant science · 2019Article
- Plants genotoxicity as pollution bioindicator in Jordan using comet assay.Physiology and molecular biology of plants : an international journal of functional plant biology · 2018Article
- Article
- Protecting DNA from errors and damage: an overview of DNA repair mechanisms in plants compared to mammals.Cellular and molecular life sciences : CMLS · 2017Review
- Moderate salt treatment alleviates ultraviolet-B radiation caused impairment in poplar plants.Scientific reports · 2016Article
- DNA damage and repair in plants - from models to crops.Frontiers in plant science · 2015Review
- Composition, roles, and regulation of cullin-based ubiquitin e3 ligases.The arabidopsis book · 2014Article
- Genetic interactions of Arabidopsis thaliana damaged DNA binding protein 1B (DDB1B) with DDB1A, DET1, and COP1.G3 (Bethesda, Md.) · 2013Article
- The conserved factor DE-ETIOLATED 1 cooperates with CUL4-DDB1DDB2 to maintain genome integrity upon UV stress.The EMBO journal · 2011Article
- Article
- Arabidopsis cockayne syndrome A-like proteins 1A and 1B form a complex with CULLIN4 and damage DNA binding protein 1A and regulate the response to UV irradiation.The Plant cell · 2010Article
- Effect of overexpression of Arabidopsis damaged DNA-binding protein 1A on de-etiolated 1.Planta · 2010Article
- CRL4s: the CUL4-RING E3 ubiquitin ligases.Trends in biochemical sciences · 2009Review
Corrections and comments
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Authors and funding
2 authors at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Damaged DNA Binding protein 1 (DDB1) is a conserved protein and a component of multiple cellular complexes. Arabidopsis has two homologues of DDB1: DDB1A and DDB1B. In this study we examine the role of DDB1A in Arabidopsis UV tolerance and DNA repair using a DDB1A null mutant (ddb1a) and overexpression lines. DDB1A overexpression lines showed higher levels of UV-resistance than wild-type in a range of assays as well as faster DNA repair. However a significant difference between wild-type plants and ddb1a mutants was only observed immediately following UV treatment in root length and photoproduct repair assays. DDB1A and DDB1B mRNA levels increased 3 h after UV exposure and DDB1A is required for UV regulation of DDB1B and DDB2 mRNA levels. In conclusion, while DDB1A is sufficient to increase Arabidopsis UV tolerance, it is only necessary for immediate response to UV damage.
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