ArticlePediatric surgery international2009
Gastroschisis: a third world perspective.
Article in Pediatric surgery international, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03185637 (Paediatric Surgery Across Sub-Saharan Africa), which is not on this map. Cited by 17 papers, 2 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Paediatric Surgery Across Sub-Saharan Africa: A Multi-Centre Prospective Cohort Study
Who cites it
17 citing papers in PubMed, 2 syntheses or guidelines pooled it, 50 citations in OpenAlex.
- Investigating the use of ultrasonography for the antenatal diagnosis of structural congenital anomalies in low-income and middle-income countries: a systematic review.BMJ paediatrics open · 2020Pooled it
- Challenges of management and outcome of neonatal surgery in Africa: a systematic review.Pediatric surgery international · 2016Pooled it
- A Pilot Study to Advance Task-Sharing of Gastroschisis Management in Uganda.Annals of global health · 2026Article
- Assessment of transfer-time and time-to-surgery as risk factors to survival in Gastroschisis (GS) in a LMIC; an eight-year review.Pediatric surgery international · 2024Article
- Improving care and survival of newborns with surgical conditions in Tanzania (TINY Tanzania): a focus on gastroschisis.Pediatric surgery international · 2024Article
- A retrospective review of gastroschisis epidemiology and referral patterns in northern Ghana.Pediatric surgery international · 2021Article
- High Abdominal Perfusion Pressure Using Umbilical Cord Flap in the Management of Gastroschisis.Frontiers in pediatrics · 2021Article
- Immediate versus silo closure for gastroschisis: Results of a large multicenter study.Journal of pediatric surgery · 2020Observational
- Challenges and Outcome of Management of Gastroschisis at a Tertiary Institution in North-Eastern Nigeria.Frontiers in surgery · 2020Article
- Developing and implementing an interventional bundle to reduce mortality from gastroschisis in low-resource settings.Wellcome open research · 2019Article
- Care of infants with gastroschisis in low-resource settings.Seminars in pediatric surgery · 2018Review
- Congenital anomalies in low- and middle-income countries: the unborn child of global surgery.World journal of surgery · 2015Review
- Complications associated with parenteral nutrition in the neonate.Clinics in perinatology · 2014Review
- Delivery room surgery: an applicable therapeutic strategy for gastroschisis in developing countries.World journal of pediatrics : WJP · 2014Article
- Prevalence of gastroschisis and its neonatal mortality in the Eastern Cape Province tertiary institutions.African journal of paediatric surgery : AJPSObservational
- Factors Affecting Survival of Newborns with Gastroschisis from a Tertiary Care Children's Hospital in India.Journal of Indian Association of Pediatric SurgeonsArticle
- Epidemiology, management and outcome of gastroschisis in Sub-Saharan Africa: Results of an international survey.African journal of paediatric surgery : AJPSArticle
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe incidence of gastroschisis is rising worldwide. In developed countries advances in neonatal intensive care (NICU) and the availability of total parenteral nutrition have improved survival for such patients, but in the third world mortality rates remain high. The aim of this study was to evaluate the impact of modern intensive care facilities on the mortality of babies with gastroschisis in Africa.
methodsA retrospective review of all neonates admitted with a diagnosis of gastroschisis at Inkosi Albert Luthuli Central Hospital in Durban over a 6-year period (2002-2007) was conducted.
resultsA total of 106 babies with gastroschisis presented during the review period. The prevalence of gastroschisis amongst neonatal surgical admissions increased from 6% in 2003 to 15% in 2007. 72% of patients weighed less than 2.5 kg at birth and 64% were premature (<37 weeks gestation). 91% were "outborn" with 71% delivered vaginally. Median maternal age was 22.6 years and 57% of mothers were primiparous. Primary abdominal wall closure was possible in 74% of patients. The overall mortality was 43% with sepsis being the leading cause. Staged closure was associated with a higher mortality than primary closure.
conclusionThe prevalence of gastroschisis amongst neonatal surgical admissions appears to be increasing. Most babies were "outborn" resulting in delays in diagnosis and referral for surgical management. Despite the availability of NICU and total parenteral nutrition the mortality remains high. Reduction in mortality will depend upon improvements in antenatal diagnosis, primary care and transportation, as well as a reduction in postsurgical sepsis.
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