Evidence map›Paper›PMID 19286958›Full record

ArticleAmerican journal of physiology. Heart and circulatory physiology2009

The shy Angeli and his elusive creature: the HNO route to vasodilation.

Nazareno Paolocci, David A Wink

Abstract readEditorialPortraitComment
In one paragraph

Article in American journal of physiology. Heart and circulatory physiology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Trial
  2. A Possible Role of Tetrodotoxin-Sensitive NaInternational journal of molecular sciences · 2024
    Article
  3. Article
  4. Nitroxyl (HNO) for treatment of acute heart failure.Current heart failure reports · 2014
    Review
  5. Article
  6. Review
  7. Article
  8. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Nazareno Paolocci
David A Wink

Funding

CHemical Biology of Nitroxyl (HNO)ZIABC011190 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI WINK, DAVID · 2009 to 2025
$2.9M
Nitroxyl cardiac effects are mediated by cAMP/PKA signalR01HL075265 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI PAOLOCCI, NAZARENO · 2005 to 2008
$1.5M
NHLBI NIH HHS R01 HL-075265
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsBiological FactorsCyclic GMPGuanylate CyclaseHumansMembrane PotentialsMuscle, Smooth, VascularNitric OxideNitritesNitrogen OxidesOxidation-ReductionPotassium Channels, Voltage-GatedReceptors, Cytoplasmic and NuclearSoluble Guanylyl CyclaseVascular ResistanceVasodilationBiological FactorsCyclic GMPendothelium-dependent hyperpolarization factorGuanylate CyclaseNitric OxideNitritesNitrogen OxidesnitroxyloxyhyponitritePotassium Channels, Voltage-GatedReceptors, Cytoplasmic and NuclearSoluble Guanylyl CyclaseVasodilator Agents

Identifiers

PMID19286958
PMCPMC2685361

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.