Evidence map›Paper›PMID 19285855›Full record

ArticleCurrent opinion in biotechnology2009

Novel genetic tools for studying food-borne Salmonella.

Helene L Andrews-Polymenis, Carlos A Santiviago, Michael McClelland

Abstract read
In one paragraph

Article in Current opinion in biotechnology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Helene L Andrews-PolymenisTexas A&M University System Health Science Center, College of Medicine, College Station, TX 77843-1114, USA. handrews@medicine.tamhsc.edu
Carlos A Santiviago
Michael McClelland

Funding

Comparative Genomics in the EnterobateriaceaeR01AI052237 · NIAID · WASHINGTON UNIVERSITY · PI WEINSTOCK, GEORGE M · 2002 to 2009
$4.1M
DETAILED RESTRICTION MAP--SALMONELLA TYPHIMURIUM GENOMER01AI034829 · NIAID · SIDNEY KIMMEL CANCER CENTER · PI MCCLELLAND, MICHAEL · 1993 to 2006
$1.9M
Salmonella Genes Associated with Colonization of Specific HostsR01AI075093 · NIAID · VACCINE RESEARCH INSTITUTE OF SAN DIEGO · PI MCCLELLAND, MICHAEL · 2009 to 2010
$928k
Salmonella Gene Expression in Complex EnvironmentsR21AI057733 · NIAID · SIDNEY KIMMEL CANCER CENTER · PI MCCLELLAND, MICHAEL · 2004 to 2004
$345k
NIAID NIH HHS R01 AI034829NIAID NIH HHS R01 AI052237NIAID NIH HHS R01 AI075093NIAID NIH HHS R21 AI057733NIAID NIH HHS R21AI057733
6 · The paper itself

Abstract

Nontyphoidal Salmonellae are highly prevalent food-borne pathogens. High-throughput sequencing of Salmonella genomes is expanding our knowledge of the evolution of serovars and epidemic isolates. Genome sequences have also allowed the creation of complete microarrays. Microarrays have improved the throughput of in vivo expression technology (IVET) used to uncover promoters active during infection. In another method, signature tagged mutagenesis (STM), pools of mutants are subjected to selection. Changes in the population are monitored on a microarray, revealing genes under selection. Complete genome sequences permit the construction of pools of targeted in-frame deletions that have improved STM by minimizing the number of clones and the polarity of each mutant. Together, genome sequences and the continuing development of new tools for functional genomics will drive a revolution in the understanding of Salmonellae in many different niches that are critical for food safety.

Indexed as

Food MicrobiologyGenome, BacterialMutagenesisOligonucleotide Array Sequence AnalysisSalmonella

Identifiers

PMID19285855
PMCPMC2762399

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.