ReviewVeterinary research
Ecological fitness and strategies of adaptation of Bartonella species to their hosts and vectors.
Review in Veterinary research. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 140 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
140 citing papers in PubMed, 3 syntheses or guidelines pooled it, 281 citations in OpenAlex.
- Pooled it
- Bartonella quintana detection among arthropods and their hosts: a systematic review and meta-analysis.Parasites & vectors · 2024Pooled it
- The Global Molecular Prevalence ofTransboundary and emerging diseases · 2023Pooled it
- Broad-spectrum molecular detection of zoonotic agents in wild micromammals: a nationwide surveillance study in the Republic of Korea.Parasites & vectors · 2026Article
- Rickettsia typhi, Bartonella henselae, and related zoonotic agents in fleas from domestic cats (Felis catus) from the Rio Grande Valley, Texas.Parasites & vectors · 2026Article
- Phlebotomine sand fly fauna characterization and Bartonella bacilliformis DNA detection in Pintomyia (Pifanomyia) robusta at the Ecuador-Peru frontier.PLoS neglected tropical diseases · 2026Article
- Asynchronous seasonal dynamics of nycteribiid bat flies and Bartonella spp. in Australian flying foxes (Pteropus spp.).Parasites & vectors · 2026Article
- Molecular Detection ofPathogens (Basel, Switzerland) · 2026Article
- First isolation and genomic insights ofFrontiers in microbiology · 2026Article
- Estimated prevalence and genetic diversity ofOne health (Amsterdam, Netherlands) · 2025Review
- Article
- Development of a multiplex serological assay to detect immunoreactivity against a novelMicrobiology spectrum · 2025Article
- Genomic characterization of eight novel Bartonella species from bats and ectoparasites reveals phylogenetic diversity and host adaptation.PLoS neglected tropical diseases · 2025Article
- Microbial diversity and functional potential of the Halobates melleus (Heteroptera: Gerridae) microbiome from the Red Sea coastline.Environmental microbiome · 2025Article
- Efficiency of anthelmintic treatment and its effect on microparasite dynamics in wildInternational journal for parasitology. Parasites and wildlife · 2025Article
- Local and global density have distinct and parasite-dependent effects on infection in wild sheep.Parasitology · 2025Article
- Genetic diversity of Bartonella spp. in rodents and fleas from Poland.Scientific reports · 2025Article
- Neuroretinitis: a comprehensive review on aetiologies, clinical manifestations, and treatment options.Eye (London, England) · 2025Review
- A One Health Zoonotic Vector Borne Infectious Disease Family Outbreak Investigation.Pathogens (Basel, Switzerland) · 2025Article
- Molecular survey of Bartonella spp., Ehrlichia spp., Anaplasma spp. and hemoplasmas in small synanthropic mammals in urban areas of Brazil's northern Amazon region.Revista brasileira de parasitologia veterinaria = Brazilian journal of veterinary parasitology : Orgao Oficial do Colegio Brasileiro de Parasitologia Veterinaria · 2025Article
80 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 6 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Bartonella spp. are facultative intracellular bacteria that cause characteristic hostrestricted hemotropic infections in mammals and are typically transmitted by blood-sucking arthropods. In the mammalian reservoir, these bacteria initially infect a yet unrecognized primary niche, which seeds organisms into the blood stream leading to the establishment of a long-lasting intra-erythrocytic bacteremia as the hall-mark of infection. Bacterial type IV secretion systems, which are supra-molecular transporters ancestrally related to bacterial conjugation systems, represent crucial pathogenicity factors that have contributed to a radial expansion of the Bartonella lineage in nature by facilitating adaptation to unique mammalian hosts. On the molecular level, the type IV secretion system VirB/VirD4 is known to translocate a cocktail of different effector proteins into host cells, which subvert multiple cellular functions to the benefit of the infecting pathogen. Furthermore, bacterial adhesins mediate a critical, early step in the pathogenesis of the bartonellae by binding to extracellular matrix components of host cells, which leads to firm bacterial adhesion to the cell surface as a prerequisite for the efficient translocation of type IV secretion effector proteins. The best-studied adhesins in bartonellae are the orthologous trimeric autotransporter adhesins, BadA in Bartonella henselae and the Vomp family in Bartonella quintana. Genetic diversity and strain variability also appear to enhance the ability of bartonellae to invade not only specific reservoir hosts, but also accidental hosts, as shown for B. henselae. Bartonellae have been identified in many different blood-sucking arthropods, in which they are typically found to cause extracellular infections of the mid-gut epithelium. Adaptation to specific vectors and reservoirs seems to be a common strategy of bartonellae for transmission and host diversity. However, knowledge regarding arthropod specificity/restriction, the mode of transmission, and the bacterial factors involved in arthropod infection and transmission is still limited.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.