ArticleGenome biology2009
Uncovering metabolic pathways relevant to phenotypic traits of microbial genomes.
Article in Genome biology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
25 citing papers in PubMed, 44 citations in OpenAlex.
- Multi-omic landscape of Mn(Ⅱ) oxidation in Achromobacter pulmonis ss21: from multicopper oxidase to metabolic support electron transfer.World journal of microbiology & biotechnology · 2026Article
- The EcoCyc database (2025).EcoSal Plus · 2025Review
- Predicting pathways for old and new metabolites through clustering.Journal of theoretical biology · 2024Article
- The EcoCyc Database (2023).EcoSal Plus · 2023Review
- Metabolomics-Driven Mining of Metabolite Resources: Applications and Prospects for Improving Vegetable Crops.International journal of molecular sciences · 2022Review
- Chemistry in Times of Artificial Intelligence.Chemphyschem : a European journal of chemical physics and physical chemistry · 2020Review
- The EcoCyc Database.EcoSal Plus · 2018Review
- Article
- The landscape of microbial phenotypic traits and associated genes.Nucleic acids research · 2016Article
- Chemoinformatics: Achievements and Challenges, a Personal View.Molecules (Basel, Switzerland) · 2016Review
- Quantifying the Relative Importance of Phylogeny and Environmental Preferences As Drivers of Gene Content in Prokaryotic Microorganisms.Frontiers in microbiology · 2016Article
- Comparative Genomics of a Bacterivorous Green Alga Reveals Evolutionary Causalities and Consequences of Phago-Mixotrophic Mode of Nutrition.Genome biology and evolution · 2015Article
- The EcoCyc Database.EcoSal Plus · 2014Article
- Article
- Inference of phenotype-defining functional modules of protein families for microbial plant biomass degraders.Biotechnology for biofuels · 2014Article
- Article
- Interactions in the microbiome: communities of organisms and communities of genes.FEMS microbiology reviews · 2014Review
- Article
- In-silico identification of phenotype-biased functional modules.Proteome science · 2012Article
- NIBBS-search for fast and accurate prediction of phenotype-biased metabolic systems.PLoS computational biology · 2012Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Identifying the biochemical basis of microbial phenotypes is a main objective of comparative genomics. Here we present a novel method using multivariate machine learning techniques for comparing automatically derived metabolic reconstructions of sequenced genomes on a large scale. Applying our method to 266 genomes directly led to testable hypotheses such as the link between the potential of microorganisms to cause periodontal disease and their ability to degrade histidine, a link also supported by clinical studies.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.