Evidence map›Paper›PMID 19283567›Full record

Trial reportThe American journal on addictions

Psychopharmacologic management of opioid-dependent women during pregnancy.

Peter R Martin, Amelia M Arria, Gabriele Fischer, Karol Kaltenbach, Sarah H Heil, Susan M Stine, Mara G Coyle, Peter Selby, Hendrée E Jones

Open access · greenAbstract readMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in The American journal on addictions. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 2 pooled it
4.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 2 syntheses or guidelines pooled it, 58 citations in OpenAlex.

  1. Guideline
  2. Intact responses to non-drug rewards in long-term opioid maintenance treatment.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2019
    Pooled it
  3. Trial
  4. Trial
  5. Trial
  6. Neonatal abstinence syndrome.Nature reviews. Disease primers · 2018
    Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 9 institutions in 3 countries.

Peter R MartinVanderbilt University School of Medicine, Nashville, Tennessee, USA. peter.martin@vanderbilt.edu
Amelia M Arria
Gabriele Fischer
Karol Kaltenbach
Sarah H Heil
Susan M Stine
Mara G Coyle
Peter Selby
Hendrée E Jones
Brown University · USJohns Hopkins Medicine · USMedical University of Vienna · ATThomas Jefferson University · USUniversity of Maryland, College Park · USUniversity of Toronto · CAUniversity of Vermont · USVanderbilt University · USWayne State University · US

Funding

YOHIMBINE AS A MODEL OF ORTHOSTATIC INTOLERANCEM01RR000095 · NCRR · VANDERBILT UNIVERSITY · PI HAAS, DAVID W · 1985 to 2008
$38.3M
Maternal Opioid Treatment: Human Experimental ResearchR01DA015764 · NIDA · JOHNS HOPKINS UNIVERSITY · PI JONES, HENDREE E · 2004 to 2008
$5.8M
Maternal Opioid Treatment: Human Experimental ResearchR01DA015738 · NIDA · THOMAS JEFFERSON UNIVERSITY · PI KALTENBACH, KAROL A · 2004 to 2008
$3.6M
Maternal Opioid Treatment: Human Experimental ResearchR01DA015713 · NIDA · VANDERBILT UNIVERSITY · PI MARTIN, PETER ROBERT · 2004 to 2008
$2.5M
Maternal Opioid Treatment: Human Experimental ResearchR01DA015832 · NIDA · WAYNE STATE UNIVERSITY · PI STINE, SUSAN M · 2004 to 2009
$2.2M
Maternal Opioid Treatment: Human Experimental ResearchR01DA018410 · NIDA · UNIVERSITY OF VERMONT &ST AGRIC COLLEGE · PI HEIL, SARAH H · 2004 to 2008
$2.2M
Maternal Opioid Treatment: Human ExperimentalR01DA018417 · NIDA · MEDICAL UNIVERSITY OF VIENNA · PI FISCHER, GABRIELE · 2004 to 2008
$1.8M
Maternal Opioid Treatment: Human Experimental ResearchR01DA015778 · NIDA · WOMEN AND INFANTS HOSPITAL-RHODE ISLAND · PI LESTER, BARRY M. · 2004 to 2009
$1.6M
Maternal Opioid Treatment: Human Experimental ResearchR01DA015741 · NIDA · ST. JOSEPH'S HEALTH CENTRE · PI SELBY, PETER L · 2004 to 2008
$643k
NCRR NIH HHS M01 RR000095NCRR NIH HHS M01RR00095NIDA NIH HHS R01 DA015713NIDA NIH HHS R01 DA015738NIDA NIH HHS R01DA015738NIDA NIH HHS R01 DA015741NIDA NIH HHS R01DA015741NIDA NIH HHS R01 DA015764NIDA NIH HHS R01 DA015778NIDA NIH HHS R01DA015778NIDA NIH HHS R01 DA015832NIDA NIH HHS R01DA 017513NIDA NIH HHS R01 DA018410NIDA NIH HHS R01DA 018410NIDA NIH HHS R01 DA018417NIDA NIH HHS R01DA15832
6 · The paper itself

Abstract

Illicit drug use during pregnancy presents complex clinical challenges, including reducing drug use and treating psychiatric disorders. Pharmacologic treatment of psychiatric disorders in a pregnant woman requires an evaluation of the balance between potential clinical benefit and the risk of potential neonatal consequences. This study describes psychiatric symptoms in 111 opioid-dependent pregnant women and their prescribed psychotropic medications. Hypomania, generalized anxiety disorder and depression were the most common disorders for which psychiatric symptoms were endorsed. Over half of women studied were prescribed some form of psychoactive medication during pregnancy. Pharmacologic vs. non-pharmacologic treatment approaches in this patient population are discussed.

Indexed as

AdultAnxiety DisordersBipolar DisorderDepressionFemaleHumansMental DisordersOpioid-Related DisordersPregnancyPregnancy ComplicationsPsychotropic DrugsPsychotropic Drugs

Identifiers

PMID19283567
PMCPMC2777700
OpenAlexW2086286607

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.