Evidence map›Paper›PMID 19281346›Full record

ArticleAIDS patient care and STDs2009

Chronicity and remission of fatigue in patients with established HIV infection.

Brian Wells Pence, Julie Barroso, James L Harmon, Jane Leserman, Naima Salahuddin, Bradley G Hammill

Abstract read
In one paragraph

Article in AIDS patient care and STDs, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Trial
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Depressive symptoms, physical symptoms, and health-related quality of life among older adults with HIV.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2019
    Article
  7. Review
  8. Article
  9. Fatigue in HIV-Infected People: A Three-Year Observational Study.Journal of pain and symptom management · 2015
    Observational
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Brian Wells PenceHealth Inequalities Program, Center for Health Policy, Duke Clinical Research Institute, Duke University School of Medicine, Durham, North Carolina 27705, USA. bpence@aya.yale.edu
Julie Barroso
James L Harmon
Jane Leserman
Naima Salahuddin
Bradley G Hammill

Funding

Pilot Project for the DTMI CRA ProgramUL1RR024128 · NCRR · DUKE UNIVERSITY · PI CALIFF, ROBERT M · 2006 to 2010
$48.1M
Fatigue in HIV-Positive PeopleR01NR008681 · NINR · DUKE UNIVERSITY · PI BARROSO, JULIE V · 2004 to 2008
$2.5M
NCRR NIH HHS 1UL1RR024128-01NINR NIH HHS 5R01NR008681NINR NIH HHS R01 NR008681
6 · The paper itself

Abstract

Fatigue is one of the most common and debilitating complaints of HIV-positive individuals, potentially leading to important functional limitations. We recruited 128 HIV-positive individuals (fatigued and nonfatigued) between March 2005 and May 2006; 66% were male, 66% were African American, 45% had greater than a high school education, 67% were unemployed, and ages ranged from 26-66 (median, 44). Every 3 months for 15 months, participants completed a 56-item self-report fatigue scale developed and validated by the authors. Participants were classified as fatigued or not fatigued at each assessment and received scores for fatigue intensity and impact of fatigue on functioning. We used linear mixed-effects models to assess longitudinal variation in fatigue scores and generalized estimating equations for binary outcomes to model predictors of fatigue remission among those fatigued at baseline. At baseline, 88% of the sample was fatigued. Fatigue measures were highly correlated across time points (rho 0.63-0.85 [intensity], 0.63-0.80 [functioning]) and showed no evidence of overall improvement, deterioration, or convergence over time. Predictors of lower fatigue scores included higher income, employment, longer time since HIV diagnosis, and antiretroviral therapy use. Those employed at baseline were likely to show improvements in fatigue while those unemployed were not. Of those fatigued at baseline, 11% experienced remission during follow-up; remission was associated with Caucasian race and employment. In summary, fatigue intensity and related functional limitations were persistent, stable, and unlikely to remit over 15 months of follow-up in this sample of patients with established HIV infection.

Indexed as

Health SurveysSeverity of Illness IndexActivities of Daily LivingAdultAgedFatigueFemaleHIV-1HIV InfectionsHumansMaleMiddle AgedPsychometricsSurveys and QuestionnairesTime Factors

Identifiers

PMID19281346
PMCPMC2856568

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.