Evidence map›Paper›PMID 19280223›Full record

ArticleVirchows Archiv : an international journal of pathology2009

A European network for virtual microscopy--design, implementation and evaluation of performance.

Mikael Lundin, Janusz Szymas, Ewert Linder, Hans Beck, Peter de Wilde, Han van Krieken, Marcial García Rojo, Ignacio Moreno, Aurelio Ariza, Sitki Tuzlali and 4 more

Registry-linked trialAbstract readMulticenter Study
PubMed Publisher
In one paragraph

Article in Virchows Archiv : an international journal of pathology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03241901 ("Aiming at Prolonging the Therapeutic Life Span of Artemisinin-based Combination Therapies), which is not on this map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03241901 phase4completednot on this mapstarted 2017, after this paper: background citation

"Aiming at Prolonging the Therapeutic Life Span of Artemisinin-based Combination Therapies (ACT) in an Era of Imminent Plasmodium Falciparum Resistance in Bagamoyo District, Tanzania - New Strategies With Old Tools"

TypeinterventionalSponsorMuhimbili University of Health and Allied SciencesRan2017 to 2018Enrolled280ConditionsMalaria,FalciparumArmsArtemether-Lumefantrine Tab 20-120mg, Primaquine Phosphate 0.25 mg/kg, Placebo
3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Whole slide imaging for educational purposes.Journal of pathology informatics · 2012
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Grid computing in image analysis.Diagnostic pathology · 2011
    Article
  10. Review
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Mikael LundinDepartment of Oncology, Institute of Clinical Medicine, University of Helsinki, Helsinki, Finland. mikael.lundin@helsinki.fi
Janusz Szymas
Ewert Linder
Hans Beck
Peter de Wilde
Han van Krieken
Marcial García Rojo
Ignacio Moreno
Aurelio Ariza
Sitki Tuzlali
Sergülen Dervişoğlu
Heikki Helin
Veli-Pekka Lehto
Johan Lundin

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Web-based virtual microscopy has enabled new applications within pathology. Here, we introduce and evaluate a network of academic servers, designed to maximize image accessibility to users from all regions of Europe. Whole-slide imaging was utilized to digitize the entire slide set (n = 154) for the slide seminars of the 21st European Congress of Pathology. The virtual slides were mirrored to five academic servers across Europe using a novel propagation method. Functionality was implemented that automatically selects the fastest server connection in order to optimize the slide-viewing speed ( http://www.webmicroscope.net/ECP2007). Results show that during 6 months of monitoring the uptime of the network was 100%. The average viewing speed with the network was 3.1 Mbit/s, as compared to 1.9 Mbit/s using single servers. A good viewing speed (>2Mbit/s) was observed in 32 of 37 countries (86%), compared to 25 of 37 (68%) using single servers. Our study shows that implementing a virtual microscopy network spanning a large geographical area is technically feasible. By utilizing existing academic networks and cost-minimizing image compression, it is also economically feasible.

Indexed as

Computer Communication NetworksLibraries, DigitalPathology, ClinicalUser-Computer InterfaceEuropeHumansImage Processing, Computer-AssistedInternetMicroscopy

Identifiers

What OpenQuestion holds

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Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.