ArticleEuropean journal of applied physiology2010
The effects of performing isometric training at two exercise intensities in healthy young males.
Article in European journal of applied physiology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers, 4 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
48 citing papers in PubMed, 4 syntheses or guidelines pooled it, 91 citations in OpenAlex.
- Effects of isometric training based on the entire population on blood pressure regulation: systematic review and meta-analysis of randomized controlled trials.Frontiers in public health · 2026Pooled it
- Isometric exercise training for blood pressure management: a systematic review and meta-analysis to optimize benefit.Hypertension research : official journal of the Japanese Society of Hypertension · 2016Pooled it
- Effect of isometric exercise on resting blood pressure: a meta analysis.Journal of human hypertension · 2010Pooled it
- Pooled it
- The implementation of a home-based isometric wall squat intervention using ratings of perceived exertion to select and control exercise intensity: a pilot study in normotensive and pre-hypertensive adults.European journal of applied physiology · 2024Trial
- Myocardial work and left ventricular mechanical adaptations following isometric exercise training in hypertensive patients.European journal of applied physiology · 2022Trial
- Blood pressure and cardiac autonomic adaptations to isometric exercise training: A randomized sham-controlled study.Physiological reports · 2022Trial
- Home-based isometric exercise training induced reductions resting blood pressure.European journal of applied physiology · 2017Trial
- The efficacy of isometric resistance training utilizing handgrip exercise for blood pressure management: A randomized trial.Medicine · 2016Trial
- Eight weeks of stretching training reduces aortic wave reflection magnitude and blood pressure in obese postmenopausal women.Journal of human hypertension · 2014Trial
- Effects of isometric handgrip training dose on resting blood pressure and resistance vessel endothelial function in normotensive women.European journal of applied physiology · 2013Trial
- Efficacy and Cost-Effective Treatment of Isometric Resistance Training for Blood Pressure Control: A Narrative Review in Healthy Individuals and People with Cardiovascular Diseases.Journal of functional morphology and kinesiology · 2026Review
- Haemodynamic adaptations to isometric handgrip versus isometric wall squat exercise training: a randomised crossover study.European journal of applied physiology · 2026Article
- Isometric Handgrip Training and Cardiovascular Risk Modulation: State of the Art.Journal of cardiovascular development and disease · 2026Review
- Article
- Pilot Study Assessing the Hemodynamic Impact and Post-Exercise Hypotension Induced by High- Versus Low-Intensity Isometric Handgrip in Patients with Ischemic Heart Disease.Journal of cardiovascular development and disease · 2025Article
- Validation of a novel multi-exercise approach to isometric resistance training in normotensive adults.European journal of applied physiology · 2025Article
- Efficacy and moderators of isometric resistance training (IRT) on resting blood pressure among patients with pre- to established hypertension: a multilevel meta-review and regression analysis.BMC sports science, medicine & rehabilitation · 2025Article
- Post-Exercise Hypotension Induced by a Short Isometric Exercise Session Versus Combined Exercise in Hypertensive Patients with Ischemic Heart Disease: A Pilot Study.Journal of functional morphology and kinesiology · 2025Article
- Effect of isometric resistance exercise on blood pressure in normotensive adults: a systematic review of randomized clinical trials.Annals of translational medicine · 2025Review
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
No previous studies have examined the effects of isometric training intensity upon resting blood pressure (BP). The aims of this study were (a) to compare the effects of leg isometric training, performed at two intensities, upon resting systolic-SBP, diastolic-DBP and mean arterial-MAP BP; and (b) to examine selected cardiovascular variables, in an attempt to explain any changes in resting BP following training. Thirty-three participants were randomly allocated to either control, high- (HI) or low-intensity (LI) training for 8 weeks. Participants performed 4 x 2 min exercise bouts 3x weekly. Resting BP was measured at baseline, 4-weeks and post-training. SBP, DBP and MAP fell significantly in both groups after training. Changes were -5.2 +/- 4.0, -2.6 +/- 2.9 and -2.5 +/- 2.2 mmHg [HI]; -3.7 +/- 3.7, -2.5 +/- 4.8 and -2.6 +/- 2.5 mmHg [LI] for SBP, DBP and MAP, respectively. There were no significant changes in BP at 4 weeks. No significant changes were observed in any of the other cardiovascular variables examined. These findings suggest that isometric training causes reductions in SBP, DBP and MAP at a range of exercise intensities, when it is performed over 8 weeks. Furthermore, it is possible to reduce resting BP using a much lower isometric exercise intensity than has previously been shown.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.