ArticleJournal of neuro-oncology2009
Stroke in cancer patients: a risk factor analysis.
Article in Journal of neuro-oncology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 1 of them a synthesis that pooled it.
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Who cites it
37 citing papers in PubMed, 1 synthesis or guideline pooled it, 96 citations in OpenAlex.
- Acute Neurological Complications of Brain Tumors and Immune Therapies, a Guideline for the Neuro-hospitalist.Current neurology and neuroscience reports · 2020Guideline
- Detection rate of FDG-PET/CT for occult cancer in patients with cryptogenic ischemic stroke.European journal of nuclear medicine and molecular imaging · 2026Observational
- Predicting cancer aetiology in patients with stroke using brain imaging alone.BMJ neurology open · 2026Article
- Intravenous thrombolysis in patients with acute ischaemic stroke and active cancer (the ITACA-stroke study).Journal of neurology · 2025Observational
- Review
- Cryptogenic embolic stroke and cancer.Frontiers in neurology · 2025Review
- Association of red blood cells, D-dimer, and 13-(S)-HODE with cancer-related ischemic stroke: a case-control study.American journal of cancer research · 2025Article
- Incidence and risk factors of ischemic stroke in patients with cancer-associated venous thromboembolism: from the Contemporary Management and Outcomes in Patients With Venous Thromboembolism Registry-2.Research and practice in thrombosis and haemostasis · 2024Article
- Clinical features and prognostic factors of patients with cancer-associated stroke.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2024Article
- Article
- Imaging of central nervous system emergencies in oncology.Emergency radiology · 2023Article
- The Risk of Ischemic and Hemorrhagic Stroke in Head and Neck Cancer: A Longitudinal Cohort Study.Cancers · 2023Article
- Bridging the Gap in Cancer-Related Stroke Management: Update on Therapeutic and Preventive Approaches.International journal of molecular sciences · 2023Review
- [Cancer-associated stroke: a study of prevalence and predictors among ischaemic stroke patients].Revista de neurologia · 2023Article
- When Two Maladies Meet: Disease Burden and Pathophysiology of Stroke in Cancer.International journal of molecular sciences · 2022Review
- Increased standardised incidence ratio of cardiovascular diseases among colorectal cancer patients.International journal of colorectal disease · 2022Article
- Cancer is associated with inferior outcome in patients with ischemic stroke.Journal of neurology · 2021Article
- Mechanisms of Ischemic Stroke in Patients with Cancer: A Prospective Study.Annals of neurology · 2021Article
- Cancer and Embolic Stroke of Undetermined Source.Stroke · 2021Review
- Ischemic Stroke in Patients with Cancer: a Retrospective Cross-Sectional Study.Journal of critical care medicine (Universitatea de Medicina si Farmacie din Targu-Mures) · 2021Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
background and purposeIn patients already suffering from cancer, the additional occurrence of stroke can aggravate the burden of the disease. The purpose of this study was to compare risk factors for haemorrhagic and ischemic strokes in cancer and non-cancer patients.
methodsA retrospective analysis, including 1,274 stroke patients admitted to a stroke unit, was conducted from 2004 to 2007. Classical risk factors for stroke and clinical outcome measures were compared between cancer and non-cancer patients.
resultsTwelve percent of stroke patients had an additional diagnosis of cancer. In the non-cancer population, 84% had ischemic and 16% had haemorrhagic strokes. In cancer patients, 86% had ischemic and 14% had haemorrhagic strokes. Vascular risk factors in cancer patients, including hypertension, atrial fibrillation, coronary vessel disease, smoking, hypercholesterolemia and diabetes mellitus, showed no difference compared to the non-cancer population. Only thrombotic events occurred more often in the cancer cohort. The most frequent cancer types were urogenital, breast and gastrointestinal. Regarding clinical outcome, cancer patients had an inferior neurological condition at discharge and a trend towards a longer stay in the stroke unit.
conclusionsThe frequency of ischemic and haemorrhagic stroke in tumour patients is similar to that in the non-cancer population. Cerebrovascular risk factors do not significantly vary between cancer and non-cancer patients. The higher frequency of thrombotic events in cancer patients may reflect a coagulation disorder, commonly found in patients with malignancy. Clinical outcome in cancer patients may be worsened by the pre-existent co-morbidity.
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