ArticleOrganogenesis2008
Muscle development and obesity: Is there a relationship?
Article in Organogenesis, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
15 citing papers in PubMed.
- Layer-Specific Architecture and Nerve Innervation of the Popliteus Muscle: Neuroanatomical Basis for Precision-Guided Interventions for the Knee Joint.Diagnostics (Basel, Switzerland) · 2026Article
- Exercise duration and detraining influence not only body weight but also histopathological changes in the white adipose tissue of young male OLETF rats as an obesity model.Physiological reports · 2025Article
- The role of obesity in physiological stress, balance, and proprioception during repetitive manual material handling tasks.PloS one · 2025Article
- Effects of Type II Diabetes on upper extremity muscle characteristics in older adults.Neuroscience letters · 2025Article
- Evidence That Skeletal Muscles Modulate HDL-Cholesterol in Metabolic Healthy Young Adults.Nutrients · 2024Observational
- Muscle fiber phenotype: a culprit of abnormal metabolism and function in skeletal muscle of humans with obesity.American journal of physiology. Endocrinology and metabolism · 2023Review
- Noninvasive NMR/MRS Metabolic Parameters to Evaluate Metabolic Syndrome in Rats.Diagnostics (Basel, Switzerland) · 2022Article
- The effect of clinically elevated body mass index on physiological stress during manual lifting activities.PloS one · 2022Article
- Level and source of fat in the diet of gestating beef cows. II. Effects on the postpartum performance of the dam and the progenyJournal of animal science · 2019Article
- Oversupplying metabolizable protein in late gestation for beef cattle: effects on postpartum ruminal fermentation, blood metabolites, skeletal muscle catabolism, colostrum composition, milk yield and composition, and calf growth performance.Journal of animal science · 2019Article
- Convergence between biological, behavioural and genetic determinants of obesity.Nature reviews. Genetics · 2017Article
- Gut microbiota can transfer fiber characteristics and lipid metabolic profiles of skeletal muscle from pigs to germ-free mice.Scientific reports · 2016Article
- Conjugated linoleic acid supplementation enhances insulin sensitivity and peroxisome proliferator-activated receptor gamma and glucose transporter type 4 protein expression in the skeletal muscles of rats during endurance exercise.Iranian journal of basic medical sciences · 2016Article
- The Link between Fetal Programming, Inflammation, Muscular Strength, and Blood Pressure.Mediators of inflammation · 2015Review
- Hertfordshire sarcopenia study: design and methods.BMC geriatrics · 2010Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The formation of skeletal muscle from the epithelial somites involves a series of events triggered by temporally and spatially discrete signals resulting in the generation of muscle fibers which vary in their contractile and metabolic nature. The fiber type composition of muscles varies between individuals and it has now been found that there are differences in fiber type proportions between lean and obese animals and humans. Amongst the possible causes of obesity, it has been suggested that inappropriate prenatal environments may 'program' the fetus and may lead to increased risks for disease in adult life. The characteristics of muscle are both heritable and plastic, giving the tissue some ability to adapt to signals and stimuli both pre and postnatally. Given that muscle is a site of fatty acid oxidation and carbohydrate metabolism and that its development can be changed by prenatal events, it is interesting to examine the possible relationship between muscle development and the risk of obesity.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.