Evidence map›Paper›PMID 19279172›Full record

ArticleJournal of clinical microbiology2009

First insight into genetic diversity of the Mycobacterium tuberculosis complex in Albania obtained by multilocus variable-number tandem-repeat analysis and spoligotyping reveals the presence of beijing multidrug-resistant isolates.

Silva Tafaj, Jian Zhang, Yolande Hauck, Christine Pourcel, Hasan Hafizi, Grigor Zoraqi, Christophe Sola

Abstract read
In one paragraph

Article in Journal of clinical microbiology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Silva TafajNational TB Reference Laboratory, University Hospital of Lung Diseases Shefqet Ndroqi, Tirana, Albania.
Jian Zhang
Yolande Hauck
Christine Pourcel
Hasan Hafizi
Grigor Zoraqi
Christophe Sola

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We characterized a set of 100 Mycobacterium tuberculosis complex clinical isolates from tuberculosis (TB) patients in Albania, typing them with a 24-locus variable-number tandem-repeat-spoligotyping scheme. Depending on the cluster definition, 43 to 49 patients were distributed into 15 to 16 clusters which were likely to be epidemiologically linked, indicative of a recent transmission rate of 28 to 34%. This result suggests that TB is under control in Albania. However, two multidrug-resistant (MDR) Beijing genotypes harboring the same S531A mutation on the rpoB gene were also found, suggesting a potential recent transmission of MDR TB. Three brand new genotypes, Albania-1 to Albania-3, are also described.

Indexed as

Bacterial Typing TechniquesGenetic VariationAlbaniaCluster AnalysisDNA, BacterialDNA-Directed RNA PolymerasesDNA FingerprintingFemaleGenotypeHumansMaleMiddle AgedMinisatellite RepeatsMolecular EpidemiologyMutation, MissenseMycobacterium tuberculosisDNA, BacterialDNA-Directed RNA PolymerasesRNA polymerase beta subunit

Identifiers

PMID19279172
PMCPMC2681852

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.