ArticleDigestive diseases and sciences2010
Doppler ultrasound of hepatic and system hemodynamics in patients with alcoholic liver cirrhosis.
Article in Digestive diseases and sciences, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 13 papers, 1 of them a synthesis that pooled it.
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Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.
- Global prevalence, incidence, and outcomes of alcohol related liver diseases: a systematic review and meta-analysis.BMC public health · 2023Pooled it
- Femoral vein Doppler ultrasound for assessing venous congestion and right heart function: a scoping review.Intensive care medicine experimental · 2026Review
- Portal vein hemodynamics measured by 4D flow MRI in predicting minimal hepatic encephalopathy in chronic hepatic schistosomiasis patients.Frontiers in medicine · 2025Article
- Abdominal perfusion pressure in critically ill cirrhotic patients: a prospective observational study.Scientific reports · 2023Observational
- Application of the optimized carbon monoxide rebreathing method for the measurement of total haemoglobin mass in chronic liver disease.Physiological reports · 2020Article
- Preoperative color Doppler ultrasonography predicts early recurrence in AFP-positive hepatocellular carcinoma.Oncology letters · 2019Article
- Changes in the Velocity of Blood in the Portal Vein in Mild Acute Pancreatitis-A Preliminary Clinical Study.Medicina (Kaunas, Lithuania) · 2019Article
- Large-volume paracentesis effects plasma disappearance rate of indo-cyanine green in critically ill patients with decompensated liver cirrhosis and intraabdominal hypertension.Annals of intensive care · 2018Article
- A sonographic Doppler study of the hepatic vein, portal vein and hepatic artery in liver cirrhosis: Correlation of hepatic hemodynamics with clinical Child Pugh score in Singapore.Ultrasound (Leeds, England) · 2017Article
- Hepatic artery resistive index (HARI) and non-alcoholic fatty liver disease (NAFLD) fibrosis score in NAFLD patients: cut-off suggestive of non-alcoholic steatohepatitis (NASH) evolution.Journal of ultrasound · 2016Observational
- Four-dimensional flow magnetic resonance imaging in cirrhosis.World journal of gastroenterology · 2016Review
- New insight into the role of NT-proBNP in alcoholic liver cirrhosis as a noninvasive marker of esophageal varices.Croatian medical journal · 2012Article
- Liver diffusivity in healthy volunteers and patients with chronic liver disease: comparison of breathhold and free-breathing techniques.Journal of magnetic resonance imaging : JMRI · 2012Article
Corrections and comments
- Erratum issuedDrazen, Zekanovic [corrected to Zekanovic, Drazen]; Neven, Ljubicic [corrected to Ljubicic, Neven]; Marko, Boban [corrected to Boban, Marko]; Marko, Nikolic [corrected to Nikolic, Marko]; Diana, Delic-Brkljacic [corrected to Delic-Brkljacic, Diana]; Petar,
Authors and funding
16 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThe progression of liver cirrhosis eventually increases cardiac output, while blood pressure and systemic vascular resistance are reduced. A complex behavior of portal hemodynamic to hepatic artery and system circulation has not yet been presented. There is a lack in knowledge about the correlation of local and systemic circulation parameters to the degree of liver failure, with respect to presence of ascites and esophageal varices. PATIENTS AND
methodsThe study sample was 76 patients hospitalized for established alcoholic liver cirrhosis. Patients were divided into groups according to Child-Pugh clinical score; grade A (n = 24), B (n = 18) and C (n = 18). Ascites was found in 28 patients and esophageal varices in 46. Portal vein flow velocity (PVFV), hepatic artery resistance index (HARI), heart and great vessels within mediastinal cavity were assessed with ultrasound devices equipped with spectral Doppler.
resultsSignificant differences in mean blood pressure, systemic vascular resistance index (SVRI) minute volume, cardiac index and PVFV were found in the group of patients with the most severe stage (C). In regard to presence of ascites statistically significant difference was observed in elevated mean blood pressure and SVRI. Correlation was found between conjugated HARI to blood pressure and to SVRI.
conclusionsIn patients with liver cirrhosis there is an inversely reciprocal relationship of conjugated HARI with PVFV, correlating to disease grade. PVFV in cirrhosis decreases and HARI values were over 0.7. Study demonstrated that combining echocardiography with abdominal Doppler ultrasound served as valuable non-invasive diagnostic insight in liver and systemic circulation among different grade of cirrhosis.
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