ArticleClinical infectious diseases : an official publication of the Infectious Diseases Society of America2009
Campylobacter genotyping to determine the source of human infection.
Article in Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 206 papers, 4 of them syntheses that pooled it.
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Who cites it
206 citing papers in PubMed, 4 syntheses or guidelines pooled it, 394 citations in OpenAlex.
- A Systematic Review and Meta-Analysis on Campylobacter Species Prevalence in Chicken in Italy.Veterinary medicine and science · 2026Pooled it
- A systematic review of source attribution of human campylobacteriosis using multilocus sequence typing.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2019Pooled it
- The Burden of Zoonoses in Kyrgyzstan: A Systematic Review.PLoS neglected tropical diseases · 2016Pooled it
- A systematic review characterizing on-farm sources of Campylobacter spp. for broiler chickens.PloS one · 2014Pooled it
- AcceleratingProceedings of the National Academy of Sciences of the United States of America · 2026Article
- Protocols for genomic epidemiology and source attribution of enteric bacteria causing diarrhoeal disease across Africa.BMJ open · 2026Article
- Comprehensive genomic insights into lineages, virulence, and antibiotic resistance profiles of Campylobacter jejuni entailing a global One Health scenario.Gut pathogens · 2026Article
- GeneScanner: profiling genetic variation across bacterial populations.Microbial genomics · 2026Article
- First molecular characterization and antimicrobial resistance profiles of Campylobacter jejuni isolated from poultry meat in Yemen.Scientific reports · 2026Article
- Everything is everywhere but Escherichia coli adapts to different niches.The ISME journal · 2026Article
- Epidemiology, antimicrobial resistance transmission, and One Health-based prevention of non-typhoidalFrontiers in microbiology · 2026Review
- Association between mink coronavirus (MCoV), Campylobacter spp., and diarrhea in farmed mink (Neogale vison).PloS one · 2026Article
- Genomic insights and survival dynamics ofFrontiers in microbiology · 2026Article
- Gut microbiome dysbiosis and functional alterations inGut microbes reports · 2026Article
- Cross-Sectional Study on Zoonotic Bacteria Carriage by Small Ruminants from Portugal's Central Region.Pathogens (Basel, Switzerland) · 2025Article
- Machine learning and statistical inference in microbial population genomics.Genome biology · 2025Review
- Antimicrobial Susceptibility ofVeterinary sciences · 2025Article
- Growth rates and metabolic traits differ by diarrhoeal manifestation inJournal of medical microbiology · 2025Article
- Virulence and infectious assessment of aMicrobiology spectrum · 2025Article
- Article
146 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
11 authors at 4 institutions in 3 countries.
Funding
Abstract
backgroundCampylobacter species cause a high proportion of bacterial gastroenteritis cases and are a significant burden on health care systems and economies worldwide; however, the relative contributions of the various possible sources of infection in humans are unclear.
methodsNational-scale genotyping of Campylobacter species was used to quantify the relative importance of various possible sources of human infection. Multilocus sequence types were determined for 5674 isolates obtained from cases of human campylobacteriosis in Scotland from July 2005 through September 2006 and from 999 Campylobacter species isolates from 3417 contemporaneous samples from potential human infection sources. These data were supplemented with 2420 sequence types from other studies, representing isolates from a variety of sources. The clinical isolates were attributed to possible sources on the basis of their sequence types with use of 2 population genetic models, STRUCTURE and an asymmetric island model.
resultsThe STRUCTURE and the asymmetric island models attributed most clinical isolates to chicken meat (58% and 78% of Campylobacter jejuni and 40% and 56% of Campylobacter coli isolates, respectively), identifying it as the principal source of Campylobacter infection in humans. Both models attributed the majority of the remaining isolates to ruminant sources, with relatively few isolates attributed to wild bird, environment, swine, and turkey sources.
conclusionsNational-scale genotyping was a practical and efficient methodology for the quantification of the contributions of different sources to human Campylobacter infection. Combined with the knowledge that retail chicken is routinely contaminated with Campylobacter, these results are consistent with the view that the largest reductions in human campylobacteriosis in industrialized countries will come from interventions that focus on the poultry industry.
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Registered trials
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