ReviewNature reviews. Genetics2009
Replication timing and epigenetic reprogramming of gene expression: a two-way relationship?
Review in Nature reviews. Genetics, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
33 citing papers in PubMed, 64 citations in OpenAlex.
- Replication Stress, Genomic Instability, and Replication Timing: A Complex Relationship.International journal of molecular sciences · 2021Review
- Dbf4 recruitment by forkhead transcription factors defines an upstream rate-limiting step in determining origin firing timing.Genes & development · 2017Article
- Spatially coordinated replication and minimization of expression noise constrain three-dimensional organization of yeast genome.DNA research : an international journal for rapid publication of reports on genes and genomes · 2016Article
- How MCM loading and spreading specify eukaryotic DNA replication initiation sites.F1000Research · 2016Review
- Understanding replication fork progression, stability, and chromosome fragility by exploiting the Suppressor of Underreplication protein.BioEssays : news and reviews in molecular, cellular and developmental biology · 2015Article
- Drosophila Rif1 is an essential gene and controls late developmental events by direct interaction with PP1-87B.Scientific reports · 2015Article
- 3D hotspots of recurrent retroviral insertions reveal long-range interactions with cancer genes.Nature communications · 2015Article
- Allele-specific genome-wide profiling in human primary erythroblasts reveal replication program organization.PLoS genetics · 2014Article
- Regulation of histone modifying enzymes by the ubiquitin-proteasome system.Biochimica et biophysica acta · 2014Review
- Looking at plant cell cycle from the chromatin window.Frontiers in plant science · 2014Review
- Alterations in replication timing of cancer-related genes in malignant human breast cancer cells.Journal of cellular biochemistry · 2013Article
- ApiAP2 transcription factor restricts development of the Toxoplasma tissue cyst.Proceedings of the National Academy of Sciences of the United States of America · 2013Article
- DNA replication timing, genome stability and cancer: late and/or delayed DNA replication timing is associated with increased genomic instability.Seminars in cancer biology · 2013Review
- Location, location, location: it's all in the timing for replication origins.Genes & development · 2013Review
- DNA replication timing and higher-order nuclear organization determine single-nucleotide substitution patterns in cancer genomes.Nature communications · 2013Article
- DNA replication stress induces deregulation of the cell cycle events in root meristems of Allium cepa.Annals of botany · 2012Article
- Mouse Rif1 is a key regulator of the replication-timing programme in mammalian cells.The EMBO journal · 2012Article
- Developing S-phase control.Genes & development · 2012Article
- Regulation of DNA replication during development.Development (Cambridge, England) · 2012Review
- Forkhead transcription factors establish origin timing and long-range clustering in S. cerevisiae.Cell · 2012Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
An overall link between the potential for gene transcription and the timing of replication in S phase is now well established in metazoans. Here we discuss emerging evidence that highlights the possibility that replication timing is causally linked with epigenetic reprogramming. In particular, we bring together conclusions from a range of studies to propose a model in which reprogramming factors determine the timing of replication and the implementation of reprogramming events requires passage through S phase. These considerations have implications for our understanding of development, evolution and diseases such as cancer.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.