ReviewFrontiers in bioscience (Landmark edition)2009
Molecular characterization of the tick-Borrelia interface.
Review in Frontiers in bioscience (Landmark edition), 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 37 citations in OpenAlex.
- Evolutionary Genetics ofCurrent issues in molecular biology · 2021Review
- Lyme Disease in Humans.Current issues in molecular biology · 2021Article
- Evolutionary ecology of Lyme Borrelia.Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases · 2020Review
- Borrelia burgdorferi protein interactions critical for microbial persistence in mammals.Cellular microbiology · 2019Review
- Microbial Invasion vs. Tick Immune Regulation.Frontiers in cellular and infection microbiology · 2017Review
- A Dual Luciferase Reporter System forFrontiers in cellular and infection microbiology · 2017Article
- Sialomes and Mialomes: A Systems-Biology View of Tick Tissues and Tick-Host Interactions.Trends in parasitology · 2016Review
- Transgene expression in tick cells using Agrobacterium tumefaciens.Experimental & applied acarology · 2015Article
- BB0323 and novel virulence determinant BB0238: Borrelia burgdorferi proteins that interact with and stabilize each other and are critical for infectivity.The Journal of infectious diseases · 2015Article
- The tick salivary protein sialostatin L2 inhibits caspase-1-mediated inflammation during Anaplasma phagocytophilum infection.Infection and immunity · 2014Article
- A dityrosine network mediated by dual oxidase and peroxidase influences the persistence of Lyme disease pathogens within the vector.The Journal of biological chemistry · 2014Article
- Population bottlenecks during the infectious cycle of the Lyme disease spirochete Borrelia burgdorferi.PloS one · 2014Article
- Hard tick factors implicated in pathogen transmission.PLoS neglected tropical diseases · 2014Review
- Identification of multilocus genetic heterogeneity in Anaplasma marginale subsp. centrale and its restriction following tick-borne transmission.Infection and immunity · 2013Article
- Borrelia burgdorferi and tick proteins supporting pathogen persistence in the vector.Future microbiology · 2013Review
- A Nod to disease vectors: mitigation of pathogen sensing by arthropod saliva.Frontiers in microbiology · 2013Review
- Genetics of Borrelia burgdorferi.Annual review of genetics · 2012Review
- A surface enolase participates in Borrelia burgdorferi-plasminogen interaction and contributes to pathogen survival within feeding ticks.Infection and immunity · 2012Article
- The hybrid histidine kinase Hk1 is part of a two-component system that is essential for survival of Borrelia burgdorferi in feeding Ixodes scapularis ticks.Infection and immunity · 2011Article
- BBA52 facilitates Borrelia burgdorferi transmission from feeding ticks to murine hosts.The Journal of infectious diseases · 2010Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
Spirochetes in the genus Borrelia are responsible for tick-borne relapsing fever and Lyme disease. Borrelia-tick interactions are highly specific as each species of Borrelia is only transmitted by one or a few closely related species of ticks. Borrelia colonize the gut or salivary glands of ticks. Several Borrelia genes required for tick colonization or transmission have been identified. Borrelia genes required for transmission are induced by a pathway controlled by the alternate sigma factors RpoN (?54) and RpoS (?S). A protein in the gut of I. scapularis ticks that functions as a receptor for B. burgdorferi has been identified. In addition, Ixodes tick saliva has proteins that alter host hemostasis and immunity, and some of these salivary proteins directly interact with Borrelia to facilitate transmission and host infection, whereas others appear to assist Borrelia indirectly by suppressing host defense mechanisms. The exciting discoveries on Borrelia-tick interactions are also being translated into novel preventive measures such as transmission blocking vaccines.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.