Evidence map›Paper›PMID 19272888›Full record

ArticleIEEE transactions on bio-medical engineering2009

Design of a new somatosensory stimulus delivery device for measuring laryngeal mechanosensory detection thresholds in humans.

Michael J Hammer

Registry-linked trialOpen access · greenAbstract readEvaluation Study
In one paragraph

Article in IEEE transactions on bio-medical engineering, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03109171 (Accuracy of the Sensory Test Performed Using the Laryngopharyngeal Endoscopic Esthesiometer and Rangefinder in Patients With Suspected Obstructive Sleep Apnoea Hypopnea), which is not on this map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
0.7field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03109171 narecruitingnot on this mapstarted 2018, after this paper: background citation

Accuracy of the Sensory Test Performed Using the Laryngopharyngeal Endoscopic Esthesiometer and Rangefinder in Patients With Suspected Obstructive Sleep Apnoea Hypopnea (OSA): a Prospective Double-blinded, Randomised, Pilot Study

TypeinterventionalSponsorFundación Neumologica ColombianaRan2018 to 2026Enrolled117ConditionsSleep Apnea, Obstructive, Larynx, Sensory DisorderArmsLaryngopharyngeal sensory test
3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 31 citations in OpenAlex.

  1. Trial
  2. Article
  3. Classifying neurogenic dysphagia as a movement disorder.Brain : a journal of neurology · 2025
    Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Reliability of a laryngo-pharyngeal esthesiometer and a method for measuring laryngo-pharyngeal mechano-sensitivity in a prospectively recruited cohort of patients.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2017
    Article
  10. Article
  11. Therapeutic intervention in oropharyngeal dysphagia.Nature reviews. Gastroenterology & hepatology · 2016
    Review
  12. Article
  13. Laryngeal Reflexes: Physiology, Technique, and Clinical Use.Journal of clinical neurophysiology : official publication of the American Electroencephalographic Society · 2015
    Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Michael J HammerDepartment of Surgery, University of Wisconsin, Madison, WI 53792, USA. hammer@surgery.wisc.edu
University of Wisconsin–Madison · US

Funding

Institutional Clinical and Translational Science Award (UW-Madison)KL2RR025012 · NCRR · UNIVERSITY OF WISCONSIN-MADISON · PI DREZNER, MARC KENNETH · 2007 to 2011
$11.1M
Laryngeal Sensorimotor Control in Parkinson's DiseaseF31DC007260 · NIDCD · UNIVERSITY OF KANSAS LAWRENCE · PI HAMMER, MICHAEL J · 2004 to 2006
$58k
NCRR NIH HHS KL2 RR025012NCRR NIH HHS RR025012NIDCD NIH HHS DC007260NIDCD NIH HHS F31 DC007260
6 · The paper itself

Abstract

Laryngeal control is essential for airway protection, breathing, deglutition, speech, and voice. Unfortunately, integration of laryngeal sensory assessment in research and clinical practice is limited by technical and practical limitations of commercially available technology. A commercial device is available, but reported limitations include procedural complexity requiring two or three individuals to operate, limited stimulus dynamic range, device generated noise, and questionable stimulus reproducibility. The objective of this study was to design a new laryngeal somatosensory stimulus delivery device that provides direct, reliable control over the timing, duration, and dynamic range of stimulus presentation, and test the device in individuals who may manifest a laryngeal sensory deficit. The new device operates silently and has more than four times greater stimulus dynamic range than the commercial device. Testing with the new device revealed laryngeal mechanosensory detection thresholds in an individual with Parkinson's disease that were seven times higher than those of healthy controls. These data would have otherwise gone undetected due to limited stimulus dynamic range in the commercial device. The new design resulted in a new assessment instrument that is simple to use for routine clinical assessment, yet sufficiently versatile for integration within rigorous clinical research protocols.

Indexed as

AdultAgedDifferential ThresholdElectric StimulationEquipment DesignHumansLaryngeal DiseasesLaryngoscopesLarynxMechanoreceptorsMechanotransduction, CellularParkinson DiseasePlethysmographyReference ValuesReproducibility of Results

Identifiers

PMID19272888
PMCPMC2680699
OpenAlexW2161231790

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.