ReviewBrain research2009
Mouse models for human otitis media.
Review in Brain research, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 28 citations in OpenAlex.
- Detecting Cochlear Synaptopathy Through Curvature Quantification of the Auditory Brainstem Response.Frontiers in cellular neuroscience · 2022Article
- Role of a novel mouse mutant of theFrontiers in neurology · 2022Article
- Resolution of otitis media in a humanized mouse model.Frontiers in genetics · 2022Article
- Innate Immunity in the Middle Ear Mucosa.Frontiers in cellular and infection microbiology · 2021Review
- Innate Immunity: Orchestrating Inflammation and Resolution of Otitis Media.Current allergy and asthma reports · 2016Review
- Otitis media induced by peptidoglycan-polysaccharide (PGPS) in TLR2-deficient (Tlr2(-/-)) mice for developing drug therapy.Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases · 2015Article
- Control of middle ear inflammatory and ion homeostasis genes by transtympanic glucocorticoid and mineralocorticoid treatments.PloS one · 2015Article
- Biofilm models of polymicrobial infection.Future microbiology · 2015Review
- Article
- A mouse model of otitis media identifies HB-EGF as a mediator of inflammation-induced mucosal proliferation.PloS one · 2014Article
- What have we learned from murine models of otitis media?Current allergy and asthma reports · 2013Review
- From in vitro to in vivo Models of Bacterial Biofilm-Related Infections.Pathogens (Basel, Switzerland) · 2013Review
- Panel 5: Microbiology and immunology panel.Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery · 2013Review
- Inner ear tissue remodeling and ion homeostasis gene alteration in murine chronic otitis media.Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology · 2013Article
- Pathological features in the LmnaDhe/+ mutant mouse provide a novel model of human otitis media and laminopathies.The American journal of pathology · 2012Article
- Otitis media in a new mouse model for CHARGE syndrome with a deletion in the Chd7 gene.PloS one · 2012Article
- Scleraxis is required for differentiation of the stapedius and tensor tympani tendons of the middle ear.Journal of the Association for Research in Otolaryngology : JARO · 2011Article
- Article
- Mucin gene expression and mouse middle ear epithelium.International journal of pediatric otorhinolaryngology · 2010Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
Abstract
Otitis media (OM) remains the most common childhood disease and its annual costs exceed $5 billion. Its potential for permanent hearing impairment also emphasizes the need to better understand and manage this disease. The pathogenesis of OM is multifactorial and includes infectious pathogens, anatomy, immunologic status, genetic predisposition, and environment. Recent progress in mouse model development is helping to elucidate the respective roles of these factors and to significantly contribute toward efforts of OM prevention and control. Genetic predisposition is recognized as an important factor in OM and increasing numbers of mouse models are helping to uncover the potential genetic bases for human OM. Furthermore, the completion of the mouse genome sequence has offered a powerful set of tools for investigating gene function and is generating a rich resource of mouse mutants for studying the genetic factors underlying OM.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.