Evidence map›Paper›PMID 19271966›Full record

ArticleJournal of neurotrauma2009

Therapeutic hypothermia: the Safar vision.

Patrick M Kochanek, Tomas Drabek, Samuel A Tisherman

Open access · greenAbstract readBiographyHistorical Article
In one paragraph

Article in Journal of neurotrauma, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 25 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Patrick M KochanekSafar Center for Resuscitation Research, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15260, USA. kochanekpm@ccm.upmc.edu
Tomas Drabek
Samuel A Tisherman
University of Pittsburgh · US

Funding

UNIVERSITY OF PITTSBURGH BRAIN TRAUMA RESEARCH CENTERP50NS030318 · NINDS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI DIXON, C EDWARD · 1995 to 2007
$8.9M
TBI, Amyloid Metabolism and Statin TherapyP01NS030318 · NINDS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI DIXON, C EDWARD · 2008 to 2010
$3.7M
ADENOSINE AND TRAUMATIC BRAIN INJURYR01NS038087 · NINDS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI KOCHANEK, PATRICK M · 1999 to 2007
$2.3M
HYPOTHERMIA AND TRAUMATIC BRAIN INJURYP20NS030318 · NINDS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI MARION, DONALD W. · 1991 to 1993
–
NINDS NIH HHS NS 30318NINDS NIH HHS NS 38087NINDS NIH HHS P01 NS030318NINDS NIH HHS R01 NS038087
6 · The paper itself

Abstract

At the 2(nd) International Brain Hypothermia conference, in Miami, the late Dr. Peter Safar was honored for his many contributions to the field of therapeutic hypothermia. Therapeutic hypothermia played a central role in his overall vision for optimized resuscitation and neurointensive care, across a large number of potential insults. The successful use of therapeutic hypothermia in comatose patients after cardiac arrest, for example, was already included in the historic first "ABCs" of resuscitation, published by Safar in 1964. This review addresses key historical events in the development and implementation of therapeutic hypothermia across a number of central nervous system insults. A discussion of future potential uses of this therapy in a variety of applications as part of the Safar vision is also presented.

Indexed as

BrainBrain InjuriesHeart ArrestHistory, 20th CenturyHumansHypothermia, InducedHypoxia-Ischemia, BrainNerve RegenerationRecovery of FunctionResuscitation

Identifiers

PMID19271966
PMCPMC2657820
OpenAlexW1972765065

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.