Evidence map›Paper›PMID 19271150›Full record

ArticleInflammation research : official journal of the European Histamine Research Society ... [et al.]2009

Detection of galectin-3 in patients with inflammatory bowel diseases: new serum marker of active forms of IBD?

Lenka Frol'ová, Karel Smetana, Dana Borovská, Andrea Kitanovicová, Klára Klimesová, Ivana Janatková, Karin Malícková, Milan Lukás, Pavel Drastich, Zdenek Benes and 5 more

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Article in Inflammation research : official journal of the European Histamine Research Society ... [et al.], 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 55 citations in OpenAlex.

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  13. The Role of Glycosylation in Inflammatory Diseases.Advances in experimental medicine and biology · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 6 institutions in 2 countries.

Lenka Frol'ováDepartment of Immunology and Gnotobiology, Institute of Microbiology, Academy of Sciences of the Czech Republic, v.v.i., Videnska 1083, Prague 4 142 20, Czech Republic.
Karel Smetana
Dana Borovská
Andrea Kitanovicová
Klára Klimesová
Ivana Janatková
Karin Malícková
Milan Lukás
Pavel Drastich
Zdenek Benes
Ludmila Tucková
Joachim C Manning
Sabine André
Hans-Joachim Gabius
Helena Tlaskalová-Hogenová
Charles University · CZCzech Academy of Sciences · CZCzech Academy of Sciences, Institute of Microbiology · CZLudwig-Maximilians-Universität München · DEInstitute of Clinical and Experimental Medicine · CZThomayer University Hospital · CZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveIt is an open question whether multifunctional galectin-3 can be a serum marker in inflammatory bowel disease.

methodsWestern blots and commercial ELISA detected and quantitated the lectin immunocytochemistry using double labeling localized it in tissue sections.

resultsSerum concentrations were significantly increased in specimen of patients with active and remission-stage ulcerative colitis and Crohn's disease, associated with emerging positivity of CD14(+) cells.

conclusionEnhanced concentration of galectin-3 in serum reflects presence of disease and points to its involvement in the pathogenesis.

Indexed as

AnimalsBiomarkersBlotting, WesternColitisColitis, UlcerativeColonCrohn DiseaseDextran SulfateElectrophoresis, Polyacrylamide GelEscherichia coliFemaleFluorescein-5-isothiocyanateFluorescent DyesGalectin 3HumansImmunohistochemistryBiomarkersDextran SulfateFluorescein-5-isothiocyanateFluorescent DyesGalectin 3LectinsLipopolysaccharide Receptors

Identifiers

PMID19271150
OpenAlexW2011002068

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.