Evidence map›Paper›PMID 19270829›Full record

ArticleJournal of Korean medical science2009

Factors associated with HIV-1 proviral DNA loads in patients with undetectable plasma RNA load.

Jun Yong Choi, Young Goo Song, Young Hwa Kim, Chang Oh Kim, Myung Soo Kim, Bum Sik Chin, Sang Hoon Han, Suk Hoon Choi, Han Sung Lee, Su Jin Jeong and 2 more

Abstract read
In one paragraph

Article in Journal of Korean medical science, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Overcoming pharmacologic sanctuaries.Current opinion in HIV and AIDS · 2013
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Jun Yong ChoiDepartment of Internal Medicine and AIDS Research Institute, BK21 Project for Medical Sciences, Yonsei University College of Medicine, Seoul, Korea.
Young Goo Song
Young Hwa Kim
Chang Oh Kim
Myung Soo Kim
Bum Sik Chin
Sang Hoon Han
Suk Hoon Choi
Han Sung Lee
Su Jin Jeong
Heekyoung Choi
June Myung Kim

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To evaluate factors associated with human immunodeficiency virus type 1 (HIV-1) proviral DNA load, we conducted a cross-sectional study of 36 chronically HIV-1-infected individuals with undetectable plasma viral RNA. We used real-time polymerase chain reaction to determine the number of HIV-1 proviral DNA copies per 10(6) peripheral blood mononuclear cells. The mean level of plasma viral RNA when the CD4+ T cell count was above 500 cells/microL without highly active antiretroviral therapy (HAART) was significantly associated with proviral DNA load at the time of undetectable plasma HIV RNA with HAART. Strategies to reduce the level of plasma viral RNA when patients' CD4+ T cell counts are above 500 cells/microL without HAART could help reduce HIV-1 proviral DNA load.

Indexed as

Anti-HIV AgentsAntiretroviral Therapy, Highly ActiveCD4-Positive T-LymphocytesCross-Sectional StudiesDNA, ViralFemaleHIV-1HIV InfectionsHumansMalePolymerase Chain ReactionProvirusesRNA, ViralAnti-HIV AgentsDNA, ViralRNA, ViralAcquired Immunodeficiency SyndromeHIVHIV InfectionsProviruses

Identifiers

PMID19270829
PMCPMC2650966

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.