ArticlePloS one2009
A genome wide survey of SNP variation reveals the genetic structure of sheep breeds.
Article in PloS one, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 160 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
160 citing papers in PubMed, 371 citations in OpenAlex.
- Evaluation of Two Commercial DNA-Based Breed Identification Tests for Pit Bull-Type Dogs in Taiwan: A Pilot Study.Animals : an open access journal from MDPI · 2026Article
- Genome-Wide SNP Characterisation of Three Kazakh Sheep Breeds: Kazakh Fat-Tailed Coarse-Wool, Degeres, and Etti Merino.Animals : an open access journal from MDPI · 2026Article
- Unveiling maternal lineages of Sopas sheep: insights from complete mitochondrial DNA cytochrome b (Cyt b) and displacement loop (D-loop) analyses.Tropical animal health and production · 2026Article
- Comprehensive analysis of population structure and genomic diversity in fifteen Anatolian sheep breeds.BMC veterinary research · 2026Article
- Assessment of genome-wide genetic variability and population divergence of four native Turkish sheep breeds.Mammalian genome : official journal of the International Mammalian Genome Society · 2026Article
- Genetic Diversity in Dutch Sheep Breeds.Animal genetics · 2026Article
- Article
- Artificial and natural selection components reveal the mechanisms of tropical sheep populations against gastrointestinal parasites.PloS one · 2026Article
- Article
- Exploring the polygenic landscape of wool traits in Turkish merinos through multi-locus GWAS approaches: Karacabey Merino.BMC veterinary research · 2025Article
- Genetic Diversity and Population Structure of Nine Local Sheep Populations Bred in the Carpathia Area of Central Europe Revealed by Microsatellite Analysis.Animals : an open access journal from MDPI · 2025Article
- Candidate Genes, Markers, Signatures of Selection, and Quantitative Trait Loci (QTLs) and Their Association with Economic Traits in Livestock: Genomic Insights and Selection.International journal of molecular sciences · 2025Review
- Preserving Biodiversity of Sheep and Goat Farming in the Apulia Region.Animals : an open access journal from MDPI · 2025Review
- Genetic diversity and adaptability of native sheep breeds from different climatic zones.Scientific reports · 2025Article
- Article
- Exploring the polygenic landscape of wool traits in Turkish Merinos through multi-locus GWAS approaches: middle Anatolian Merino.Scientific reports · 2025Article
- BbGSD: Black-boned Sheep Genome SNP Database.Database : the journal of biological databases and curation · 2025Article
- Estimation of breed composition of South African sheep affected with wet carcass syndrome.Frontiers in genetics · 2025Article
- Genetic diversity in German Pomeranian Coarsewool sheep and the possibility of breeding for maedi-visna resistance.Archives animal breeding · 2025Article
- Investigation of growth traits in Turkish Merino lambs using multi-locus GWAS approaches: Middle Anatolian Merino.BMC veterinary research · 2024Article
100 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
17 authors at 9 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The genetic structure of sheep reflects their domestication and subsequent formation into discrete breeds. Understanding genetic structure is essential for achieving genetic improvement through genome-wide association studies, genomic selection and the dissection of quantitative traits. After identifying the first genome-wide set of SNP for sheep, we report on levels of genetic variability both within and between a diverse sample of ovine populations. Then, using cluster analysis and the partitioning of genetic variation, we demonstrate sheep are characterised by weak phylogeographic structure, overlapping genetic similarity and generally low differentiation which is consistent with their short evolutionary history. The degree of population substructure was, however, sufficient to cluster individuals based on geographic origin and known breed history. Specifically, African and Asian populations clustered separately from breeds of European origin sampled from Australia, New Zealand, Europe and North America. Furthermore, we demonstrate the presence of stratification within some, but not all, ovine breeds. The results emphasize that careful documentation of genetic structure will be an essential prerequisite when mapping the genetic basis of complex traits. Furthermore, the identification of a subset of SNP able to assign individuals into broad groupings demonstrates even a small panel of markers may be suitable for applications such as traceability.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.