Evidence map›Paper›PMID 19270182›Full record

ReviewThe journals of gerontology. Series A, Biological sciences and medical sciences2009

Indications, labeling, and outcomes assessment for drugs aimed at improving functional status in older persons: a conversation between aging researchers and FDA regulators.

Working Group on Functional Outcome Measures for Clinical Trials, Shalender Bhasin, Mark A Espeland, William J Evans, Luigi Ferrucci, Linda P Fried, Thomas M Gill, Marco Pahor, Stephanie Studenski, Jack Guralnik and 5 more

Abstract readReview
In one paragraph

Review in The journals of gerontology. Series A, Biological sciences and medical sciences, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Trial
  2. Trial
  3. Review
  4. Review
  5. Comparative Approaches to Understanding the Relation Between Aging and Physical Function.The journals of gerontology. Series A, Biological sciences and medical sciences · 2016
    Review
  6. Article
  7. [Drug therapy in the elderly].Zeitschrift fur Gerontologie und Geriatrie · 2014
    Article
  8. Medication use and functional status decline in older adults: a narrative review.The American journal of geriatric pharmacotherapy · 2011
    Review
  9. Article
  10. Novel strategies for improving physical function.Hormone research in paediatrics · 2011
    Article
  11. Article
  12. Article
  13. Target population for clinical trials.The journal of nutrition, health & aging · 2009
    Article
  14. What are the outcomes of treatment among patients with sarcopenia?The journal of nutrition, health & aging · 2009
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Working Group on Functional Outcome Measures for Clinical TrialsBoston University School of Medicine, Boston, MA, USA.
Shalender Bhasin
Mark A Espeland
William J Evans
Luigi Ferrucci
Linda P Fried
Thomas M Gill
Marco Pahor
Stephanie Studenski
Jack Guralnik
Susan Nayfield
Sergei Romashkin
Robert Perlstein
Laurie Burke
Mary Parks

Funding

University of Florida Older Americans Independence Center (OAIC)P30AG028740 · NIA · UNIVERSITY OF FLORIDA · PI Karyn A Esser, Todd Manini · 2007 to 2026
$22.8M
Research Training in Disability &Disabling DisordersK24AG021507 · NIA · YALE UNIVERSITY · PI GILL, THOMAS MICHAEL · 2003 to 2012
$1.6M
NIA NIH HHS K24 AG021507NIA NIH HHS P30 AG028740
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Activities of Daily LivingOutcome Assessment, Health CareUnited States Food and Drug AdministrationAgedAged, 80 and overAgingCognition DisordersDose-Response Relationship, DrugFemaleFrail ElderlyGeriatric AssessmentHumansInterdisciplinary CommunicationMalePharmaceutical PreparationsPhysical FitnessPharmaceutical Preparations

Identifiers

PMID19270182
PMCPMC2657175

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.