ArticleApplied and environmental microbiology2009
Rapid identification of genes encoding DNA polymerases by function-based screening of metagenomic libraries derived from glacial ice.
Article in Applied and environmental microbiology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.
What it found
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Who cites it
37 citing papers in PubMed, 107 citations in OpenAlex.
- Unearthing the genetic resources of Arabian sea seamount and metagenomic insights into phosphate cycling genes for next generation plant biostimulants.Scientific reports · 2025Article
- Molecular Characterization of a DNA Polymerase fromInternational journal of molecular sciences · 2022Article
- A multi-omic screening approach for the discovery of thermoactive glycoside hydrolases.Extremophiles : life under extreme conditions · 2021Article
- Functional Metagenomic Screening for Antimicrobial Resistance in the Oral Microbiome.Methods in molecular biology (Clifton, N.J.) · 2021Article
- A New High-Throughput Screening Method to Detect Antimicrobial Volatiles from Metagenomic Clone Libraries.Antibiotics (Basel, Switzerland) · 2020Article
- The Variety and Inscrutability of Polar Environments as a Resource of Biotechnologically Relevant Molecules.Microorganisms · 2020Review
- Biochemical Characteristics of Microbial Enzymes and Their Significance from Industrial Perspectives.Molecular biotechnology · 2019Review
- Metagenomics in ophthalmology: current findings and future prospectives.BMJ open ophthalmology · 2019Review
- Recent Advances in Function-based Metagenomic Screening.Genomics, proteomics & bioinformatics · 2018Review
- The evolving interface between synthetic biology and functional metagenomics.Nature chemical biology · 2018Review
- Model-enabled gene search (MEGS) allows fast and direct discovery of enzymatic and transport gene functions in the marine bacteriumThe Journal of biological chemistry · 2017Article
- ExoMeg1: a new exonuclease from metagenomic library.Scientific reports · 2016Article
- Molecular Detection and Environment-Specific Diversity of Glycosyl Hydrolase Family 1 β-Glucosidase in Different Habitats.Frontiers in microbiology · 2016Article
- deFUME: Dynamic exploration of functional metagenomic sequencing data.BMC research notes · 2015Article
- Improved cultivation and metagenomics as new tools for bioprospecting in cold environments.Extremophiles : life under extreme conditions · 2015Review
- Synthetic biology approaches to improve biocatalyst identification in metagenomic library screening.Microbial biotechnology · 2015Review
- Discovery of new protein families and functions: new challenges in functional metagenomics for biotechnologies and microbial ecology.Frontiers in microbiology · 2015Review
- Functional Screening of Hydrolytic Activities Reveals an Extremely Thermostable Cellulase from a Deep-Sea Archaeon.Frontiers in bioengineering and biotechnology · 2015Article
- Current and future resources for functional metagenomics.Frontiers in microbiology · 2015Article
- Metagenomics: Retrospect and Prospects in High Throughput Age.Biotechnology research international · 2015Review
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Small-insert and large-insert metagenomic libraries were constructed from glacial ice of the Northern Schneeferner, which is located on the Zugspitzplatt in Germany. Subsequently, these libraries were screened for the presence of DNA polymerase-encoding genes by complementation of an Escherichia coli polA mutant. Nine novel genes encoding complete DNA polymerase I proteins or domains typical of these proteins were recovered.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.