Trial reportAmerican journal of obstetrics and gynecology2009
Magnetic resonance imaging and transvaginal ultrasound for determining fibroid burden: implications for research and clinical care.
Trial report in American journal of obstetrics and gynecology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00290251 (Evaluation of Whether the Selective Progesterone Receptor Modulator CDB-2914 Can Shrink Leiomyomata), which is not on this map. Cited by 26 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Evaluation of Whether the Selective Progesterone Receptor Modulator CDB-2914 Can Shrink Leiomyomata
Who cites it
26 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Molecular Insights in Uterine Leiomyosarcoma: A Systematic Review.International journal of molecular sciences · 2022Pooled it
- Accuracy of Ultrasound in Estimating Uterine Fibroid Size: A Correlative Study With Intraoperative Findings.Cureus · 2026Article
- Diagnosis and classification of uterine fibroids.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2025Review
- Associations Between Earlier Menarche and Fibroid Severity in Individuals Seeking Hysterectomy.Journal of women's health (2002) · 2025Observational
- A four-gene signature identified by integrated transcriptomic analysis for differential diagnosis and prognosis of uterine smooth muscle tumors.Frontiers in oncology · 2025Article
- Increased incidence of uterine leiomyoma in young females with depression: An observational study.iScience · 2024Article
- Article
- Article
- Multiparametric quantitative magnetic resonance imaging of uterine fibroids for prediction of growth rate-a pilot study.Quantitative imaging in medicine and surgery · 2024Article
- Association of genital talc and douche use in early adolescence or adulthood with uterine fibroids diagnoses.American journal of obstetrics and gynecology · 2023Article
- Contained Power Morcellation in Laparoscopic Uterine Myoma Surgeries: A Brief Review.Healthcare (Basel, Switzerland) · 2023Review
- Associations of Pregnancy Per- and Polyfluoroalkyl Substance Concentrations and Uterine Fibroid Changes across Pregnancy: NICHD Fetal Growth Studies - Singletons Cohort.Environmental health perspectives · 2023Article
- Sonographic Monitoring of Growth of Uterine Myomas in Untreated Women and Respective Influence Factors.Geburtshilfe und Frauenheilkunde · 2023Article
- An autophagy-related diagnostic biomarker for uterine fibroids: FOS.Frontiers in medicine · 2023Article
- Incorporating 3D reconstruction in preoperative surgical planning of Multiple Myomectomy.Facts, views & vision in ObGyn · 2022Article
- Uterine fibroid incidence and growth in an ultrasound-based, prospective study of young African Americans.American journal of obstetrics and gynecology · 2020Observational
- Advanced 3D Imaging of Uterine Leiomyoma's Morphology by Propagation-based Phase-Contrast Microtomography.Scientific reports · 2019Article
- Phthalates exposure and uterine fibroid burden among women undergoing surgical treatment for fibroids: a preliminary study.Fertility and sterility · 2019Article
- Transethnic and race-stratified genome-wide association study of fibroid characteristics in African American and European American women.Fertility and sterility · 2018Article
- Optimizing research in symptomatic uterine fibroids with development of a computable phenotype for use with electronic health records.American journal of obstetrics and gynecology · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
objectivesTo compare magnetic resonance and ultrasound imaging for uterine fibroid measurement. STUDY
designEighteen women undergoing hysterectomy for symptomatic fibroids underwent preoperative pelvic ultrasound and magnetic resonance imaging. Resected fibroids were correlated with the images. Weighted kappa agreement statistics and Spearman correlations for patient characteristics were calculated.
resultsMagnetic resonance imaging identified 121 of 151 pathologically confirmed fibroids, yielding 91% positive predictive value (95% confidence interval [CI], 85-95) and 80% sensitivity (95% CI, 73-86). Positive predictive value and sensitivity for ultrasound were 97% (95% CI, 89-100) and 40% (95% CI, 32-48), respectively. Mean diameter-equivalent discrepancies between imaging and pathologic measurements were 0.51 +/- 0.68 cm for magnetic resonance imaging and 0.76 +/- 0.88 cm for ultrasound. kappa statistics comparing imaging to pathology showed better agreement for magnetic resonance than ultrasound (kappa = 0.60 vs 0.36). The number of fibroids detected by magnetic resonance imaging predicted measurement errors (r = 0.76; P = .0002).
conclusionSuperior sensitivity and minimal measurement discrepancies suggest magnetic resonance imaging may be preferentially used for fibroid assessment in clinical research.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.